Protein Alignment ort and Rdl

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_316070.4
• Gene: Rdl / 1276697
• VectorBaseID: AGAMI1_011163
• Length: 555
• Species: Anopheles gambiae
• Alignment Length: 518
• Identity: 142/518 - (27%)
• Similarity: 225/518 - (43%)
• Gaps: 83/518 - (16%)

  Fly    21 GEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWK 85
            |.....:.|:.||......|||...|...|.|..|...:.|:.:.|:.|..|.:..|.:|.|.|.
Mosquito    46 GSMLGDVNISAILDSFSVGYDKRVRPNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWT 110

  Fly    86 DHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLT 150
            |.||...:....|...:..:::||:|.||:||.|.|...|...|..|.::.::...:|...::||
Mosquito   111 DPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRIHHSGSITRSIRLT 175

  Fly   151 LKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW-DPTTPLVVDENIELPQVALIRNETADC 214
            :..||.||...:|.|.|.|.:::||..:|..|:.:.| |..:.:.:...:||||..::.:.....
Mosquito   176 ITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWKDGLSSVGMSSEVELPQFRVLGHRQRAT 240

  Fly   215 TQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTL 279
            ....:|||::.|.......|.:.||:...|||:.:|||:||||||:...|.||||.||||::||:
Mosquito   241 EINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTM 305

  Fly   280 STQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKP--MAY------- 335
            :|..:.:.::||.:||:|::|.::..|.|.||.:|:||..:..:.....:.|.  ||.
Mosquito   306 TTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQK 370

  Fly   336 -----------PPKPVAGDGPKKEGEG-------APPGGSNSTASKQQATMLPLADEKIEKIEKI 382
                       ||.|||.|.....|.|       .|.....|.:...|.....:.......:..:
Mosquito   371 KQQQADANHPPPPPPVASDHSHGHGHGHSHTHQHTPKQQMGSRSGTMQNVPPNMGSRGCSIVGPL 435

  Fly   383 FDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTI------------APPP------- 428
            |.|:         ..:|..|...:.|.         .|..||            .|||
Mosquito   436 FQEV---------RFKVHDPKAHSKGG---------TLENTINGGRGGGQPGGGGPPPGGPPGGG 482

  Fly   429 ---PPPQPAAPEPELPKPK-------LTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
               |..:.|||:..:...|       :||:.        ||:.||::||..|...|.:||.::
Mosquito   483 GGGPDEESAAPQHLIHPGKDINKLLGITPSD--------IDKYSRIVFPVCFVCFNLMYWIIY 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	140/506 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	51/184 (28%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
Rdl	XP_316070.4	LIC	56..537	CDD:455710	140/506 (28%)
		LGIC_ECD_GABAR_RDL-like	78..261	CDD:349809	50/182 (27%)
		Cys-loop	180..194	CDD:349809	6/13 (46%)