Protein Alignment ort and alka

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_061511191.1
• Gene: alka / 1272496
• VectorBaseID: AGAMI1_009367
• Length: 466
• Species: Anopheles gambiae
• Alignment Length: 497
• Identity: 137/497 - (27%)
• Similarity: 236/497 - (47%)
• Gaps: 85/497 - (17%)

  Fly     7 ILVIC----TICMKHYAKGEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSI 67
            :||:|    .:..|:|       :|....:||||..:  ::|||.::|.|.:|.|.:.|:.::||
Mosquito    22 LLVMCLLKEVVAAKNY-------TLKPRVVLPEDYVK--EVRPPSQKGSPVVVEFSIFVVDINSI 77

  Fly    68 DENSMTYVADVFFAQTWKDHRLRLPENMTQE---YRLLEVDWLKNMWRPDSFFKNAKSVTFQTMT 129
            :...|.:..|:|..|.|.:.||.|.:::.:|   :.:|..::..|:|:||.:|.|:|.....|:|
Mosquito    78 NVEDMDFRVDMFVHQKWVESRLDLHDDIFEEGDDHVILPPEFFDNLWQPDPYFLNSKISEIATLT 142

  Fly   130 IPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLV 194
            .....:.|||:.|:.|...:...::|.|.|.:||.|.|.|.:.:||.|:....:..:|
Mosquito   143 HKFSSVTLYKNSTVRYACMMHAIIACQMEFQLYPMDIQICPIYIESFSYHNQKIRLKW------- 200

  Fly   195 VDENIEL-PQVALIRNETADCTQVYST--------GNFTCLEVVFTLKRRLVYYVFNTYIPTCMI 250
            .|..:.: |::.|::.......|:..|        |||:.|.|.|..:|::.:::..|:.|:.::
Mosquito   201 ADNGVTINPELKLLQYNLGQPLQLEETDGYMPEKYGNFSRLAVYFRFERQIGHHLIQTFAPSSLV 265

  Fly   251 VIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALM 315
            |::||.|||:..:|.|.||||.||.:|||.|.....::.:|||:|:||:|.:|:.|.:|||.||.
Mosquito   266 VMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGMRADIPPVAYVKALDLWMAGCMLFVFSALG 330

  Fly   316 EYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIE 380
            |:.::.::  |......:...||                             :||:....:||.:
Mosquito   331 EFVVVKVL--DVQYQYQVNKVPK-----------------------------VLPMRISAMEKGQ 364

  Fly   381 KI-----FDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAP--EP 438
            .:     ::..|.|          |||......|..|.|.|   |.....|.||.|....|  ..
Mosquito   365 CVGTVANWEGGTVN----------VRPRKPTQTPTTPGQVS---LQGNGGPQPPLPPTKQPTRRQ 416

  Fly   439 ELPKPKLTPAQERLKRAIY--IDRSSRVLFPALFASLNGIYW 478
            .:.....|.....:::.::  ||:.|||:||.||.....:||
Mosquito   417 SILSVAWTDTDTGIEKIMWREIDKMSRVVFPGLFLVFVVLYW 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	131/469 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	53/195 (27%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
alka	XP_061511191.1	None