Protein Alignment ort and Gabra5

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001349090.1
• Gene: Gabra5 / 110886
• MGIID: 95617
• Length: 463
• Species: Mus musculus
• Alignment Length: 507
• Identity: 147/507 - (28%)
• Similarity: 227/507 - (44%)
• Gaps: 94/507 - (18%)

  Fly     1 MVFQIIILVICTICMKHY---------AKGEFQQSLAI-TDILPEDIKRYD-KMRPPKKEGQPTI 54
            |...:::..|......|:         .:.|...::.| |.||...:..|| ::||...| :.|.
Mouse    11 MTQTLLVFCISMTLSSHFGFSQMPTSSVQDETNDNITIFTRILDGLLDGYDNRLRPGLGE-RITQ 74

  Fly    55 VYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRL-------RLPENMTQEYRLLEVDWLKNMWR 112
            |...:.|.....:.:..|.|..||||.|:|||.||       |||.|     .||    ...:|.
Mouse    75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLN-----NLL----ASKIWT 130

  Fly   113 PDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLS 177
            ||:||.|.|......||.||..:.|..|.|:||.::||:...|.|....:|.|...|.|:..|.:
Mouse   131 PDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYA 195

  Fly   178 HTTDDLIFQW---DPTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYY 239
            :...::::.|   ...:.:|.::...|.|..|:...........|||.:|.:...|.|||::.|:
Mouse   196 YPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYF 260

  Fly   240 VFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMS 304
            |..||:|..|.||:|.||||:..|:.|||...|||::||::|....:::|||.|:|..|:|.|::
Mouse   261 VIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIA 325

  Fly   305 VCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATML 369
            ||..|||.||:|:..:|.            :..:..|.|| ||..|.|
Mouse   326 VCYAFVFSALIEFATVNY------------FTKRGWAWDG-KKALEAA----------------- 360

  Fly   370 PLADEKIEKIEKIFDEMTKNRRI-VTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQP 433
                 ||:|.|:   |:..|:.. ..||.::..||.      ||:::              ||..
Mouse   361 -----KIKKKER---ELILNKSTNAFTTGKLTHPPN------IPKEQ--------------PPAG 397

  Fly   434 AAPEP----ELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            .|..|    :..:.|...:::.......||:.||::||.||.:.|.:||..:
Mouse   398 TANAPTVSIKASEEKTAESKKTYNSISKIDKMSRIVFPILFGTFNLVYWATY 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	141/465 (30%)
		Neur_chan_LBD	38..235	CDD:280998	63/207 (30%)
		Neur_chan_memb	243..>334	CDD:280999	38/90 (42%)
Gabra5	NP_001349090.1	LIC	15..449	CDD:273305	146/501 (29%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	63/207 (30%)
		Cys-loop	173..187	CDD:349839	4/13 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..408		7/40 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810