Protein Alignment ort and gabrr1

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_017949821.2
• Gene: gabrr1 / 100497913
• XenbaseID: XB-GENE-1013743
• Length: 478
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 144/476 - (30%)
• Similarity: 213/476 - (44%)
• Gaps: 104/476 - (21%)

  Fly    35 EDIKRYD----KMRPPKKEGQPTI-VYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLP-- 92
            |.:.|.|    .|||  ..|.|.| |...|.|..||||.|..|.:...::....|||.||..|
 Frog    77 EQLLRIDDHDFTMRP--GFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSS 139

  Fly    93 --ENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSC 155
              ::||.:.||     :|.:|.||.||.::|.......|..|..:.:..|..:||.:::|:...|
 Frog   140 NNQSMTFDGRL-----VKKIWVPDMFFVHSKRSFIHDTTTDNIMLRVQPDGKVLYSLRVTVTAMC 199

  Fly   156 IMNFAIYPHDTQECKLQMESLSHTTDDLIFQW-DPTTPLVVDENIELPQVALIRNETADCTQVY- 218
            .|:|:.:|.|||.|.|::||.::|.|||:..| :....|..|:.|.|.|..:....|......|
 Frog   200 NMDFSRFPLDTQSCSLEIESYAYTEDDLMLYWKNGNESLKTDDRISLSQFLIQEFHTTTRLAFYS 264

  Fly   219 STGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQH 283
            |||.:..|.:.|||:|.:.:::..||.|..::|::|||||||...||||||.||:|::||:||..
 Frog   265 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAAPARVPLGITTVLTMSTII 329

  Fly   284 AKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLS-----------------DTPIPK 331
            ....:|:|.|||:||||.::.|..||||::::||..:|.:.:                 ..|.|:
 Frog   330 TGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKMREKYPCTCGVPQPR 394

  Fly   332 PMAYPPKPVAGDGPKKEGEGAPPGG-SNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTT 395
            .|.        |....:||....|. .:....|:...|:.||         :..|...|||  .:
 Frog   395 SMM--------DSSYSDGEVNNLGNYVSENGDKEDRIMVQLA---------LNAERNSNRR--KS 440

  Fly   396 TRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDR 460
            .|..|...:|...                                                 ||:
 Frog   441 QRAYVSMRIDTHA-------------------------------------------------IDK 456

  Fly   461 SSRVLFPALFASLNGIYWCVF 481
            .||::|||.:...|.||||:|
 Frog   457 YSRLIFPASYILFNLIYWCIF 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	143/474 (30%)
		LGIC_ECD_HisCl	51..235	CDD:349793	64/190 (34%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
gabrr1	XP_017949821.2	LIC	76..474	CDD:455710	140/471 (30%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	64/189 (34%)
		Cys-loop	199..213	CDD:349806	7/13 (54%)