Protein Alignment ort and glra2

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_004912302.1
• Gene: glra2 / 100494348
• XenbaseID: XB-GENE-958032
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 166/494 - (33%)
• Similarity: 253/494 - (51%)
• Gaps: 69/494 - (13%)

  Fly    14 CMKHYAKGEFQQSLAITDILPEDIKR---YDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYV 75
            |.:|..:......::.:|.|.:.:.|   ||....|..:|.|..|..::.:....||.|.:|.|.
 Frog    27 CKEHDTRSGKSPPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYR 91

  Fly    76 ADVFFAQTWKDHRL---RLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWL 137
            .::|..|||.|.||   ..|::...    |:...|.::|:||.||.|.|...|..:|..|..:.:
 Frog    92 VNIFLRQTWNDPRLSYSEYPDDSLD----LDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRI 152

  Fly   138 YKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELP 202
            :|:..:||.::|||.|||.|:...:|.|.|.|.:|:||..:|.:||||:|..|:|:.|.:.:.||
 Frog   153 FKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWLSTSPVQVADGLTLP 217

  Fly   203 QVAL-IRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAP 266
            |..| ..||...||:.|:||.|||:||.|.|:|::.||:...|||:.:|||:|||||||..:|||
 Frog   218 QFILKEENELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 282

  Fly   267 ARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPK 331
            |||.||:|::||::||.:.|::|||.|||:||:|.:|:||.:|||.||:||..:|.|
 Frog   283 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV-------- 339

  Fly   332 PMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTT 396
                         .::..|..    ......|:|:..:.:.:|.:|.:.::....:.:.....|.
 Frog   340 -------------SRQHKEFL----RLRRRQKRQSKTVLVGNESVESVRRMNGLRSTDSSAYGTL 387

  Fly   397 RRVVRPPLDADGPWIPRQESR-------------------IILTPTIAPPPPPPQPAAPEPELPK 442
            .::..|.|..:.   ..:|||                   :..||   |.||||||  .:.:..|
 Frog   388 NQIYNPSLREED---VARESRFNFSGYGMGHCLQVKDGTAVKATP---PIPPPPQP--KDADSIK 444

  Fly   443 PKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            .|..   :|.||   ||..||..||..|...|..||..:
 Frog   445 KKFV---DRAKR---IDTISRAAFPLAFLIFNIFYWITY 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	164/475 (35%)
		LGIC_ECD_HisCl	51..235	CDD:349793	71/187 (38%)
		Cys-loop	155..169	CDD:349793	5/13 (38%)
glra2	XP_004912302.1	LIC	44..477	CDD:273305	164/475 (35%)