Protein Alignment ort and gabra1

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 460
• Identity: 142/460 - (30%)
• Similarity: 219/460 - (47%)
• Gaps: 69/460 - (15%)

  Fly    30 TDILPEDIKRYD-KMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            |.||...:..|| ::||...| :.|.|...:.|.....:.::.|.|..||||.|.|:|.||:...
 Frog    42 TRILDRLLDGYDNRLRPGLGE-RVTEVNTDIFVTSFGPVSDHDMEYTIDVFFRQGWRDERLKFKG 105

  Fly    94 NMTQEYRLLEVDWL--KNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCI 156
            .||    :|.::.|  ..:|.||:||.|.|......||:||..:.:.:|.|:||.::||::..|.
 Frog   106 PMT----VLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECP 166

  Fly   157 MNFAIYPHDTQECKLQMESLSHTTDDLIFQW--DPTTPLVV-DENIELPQVALIRNETADCTQVY 218
            |:...:|.|...|.|:..|.::|..::::.|  :|:..:|| ::...|.|..|:....|......
 Frog   167 MHLEDFPMDAHACPLKFGSYAYTRAEVVYSWTREPSLSVVVAEDGSRLNQYDLLGQTVASGIVQS 231

  Fly   219 STGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQH 283
            |||.:..:...|.|||::.|:|..||:|..|.||:|.||||:..|:.|||...|||::||::|..
 Frog   232 STGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLS 296

  Fly   284 AKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKE 348
            ..:::|||.|:|..|:|.|::||..|||.||:|:..:|....     :..|:..|.|..:.|||.
 Frog   297 ISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK-----RGYAWDGKSVVPEKPKKV 356

  Fly   349 GEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPR 413
            .:                   ||              :.||....:.|...  ||.      |||
 Frog   357 KD-------------------PL--------------IKKNNTYASATANY--PPT------IPR 380

  Fly   414 QE--SRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGI 476
            ..  :.|..:.||.|....|:|...||          ::.......|||.||:.||.||.:.|.:
 Frog   381 DPGLATIAKSATIEPKDIEPKPKPAEP----------KKTFNSVSKIDRLSRIAFPLLFGTFNLV 435

  Fly   477 YWCVF 481
            ||..:
 Frog   436 YWATY 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	141/457 (31%)
		LGIC_ECD_HisCl	51..235	CDD:349793	57/188 (30%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
gabra1	XP_031754594.1	LIC	11..440	CDD:455710	142/458 (31%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	60/197 (30%)
		Cys-loop	165..179	CDD:349835	4/13 (31%)