Protein Alignment ort and gabra6

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_031754593.1
• Gene: gabra6 / 100488862
• XenbaseID: XB-GENE-6049732
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 137/464 - (29%)
• Similarity: 216/464 - (46%)
• Gaps: 63/464 - (13%)

  Fly    29 ITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            ||.||...:..||....|...|..|.|...:.|.....:.:..|.|..|:||.|||.|.||:. :
 Frog    32 ITRILDRLLDGYDNRLRPSFGGPVTEVKTDIYVTSFGPVSDVDMEYTMDIFFRQTWVDERLKF-D 95

  Fly    94 NMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMN 158
            ..|:..||..: .:..:|.||:||:|.|......||.||....:.::.|:||.::||:|..|.|.
 Frog    96 GPTEILRLNNL-MVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTVLYTMRLTIKAECPMR 159

  Fly   159 FAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPL----VVDENIELPQVALIRNETADCTQVYS 219
            ...:|.|...|.|:..|.::...::::.| ...||    |.:|:..|.|..|:..:.:..|.:.:
 Frog   160 LMNFPMDGHACPLKFGSYAYPKSEIVYTW-KKGPLYSVEVPEESSSLLQYDLVGQKVSSETLLSN 223

  Fly   220 TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHA 284
            ||.::...|:|.|:|::.||:.:||||..|.|::|.|.|||..|:.|||...|:|::||::|...
 Frog   224 TGEYSLQVVMFFLQRKIGYYIIHTYIPCSMTVVLSQVVFWINKESVPARTVAGITTVLTMTTLSI 288

  Fly   285 KSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPK--PVAGDGPKK 347
            .::.|.|.|||..|:|.|::||..|||.||:|:..:| ..::..|.|.|....|  .:|....:.
 Frog   289 SARHSFPKVSYATAMDWFIAVCFAFVFSALIEFAAVN-YFTNLQIQKTMMKAAKKAALAAATARA 352

  Fly   348 EGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPW-- 410
            |.|......||....|           :|..:....::.|:...           ||..|.|:
 Frog   353 ENEFVTLSDSNCNLKK-----------RINSVASQGNQSTEGDL-----------PLYEDSPYNE 395

  Fly   411 ---IPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFAS 472
               ||.::.  :|:.|                      |.:|.  .....||:.:|:|||..||.
 Frog   396 QTDIPTRDH--MLSDT----------------------TSSQH--TGTSKIDKYARILFPLSFAG 434

  Fly   473 LNGIYWCVF 481
            .|.:||.|:
 Frog   435 FNLVYWVVY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	134/460 (29%)
		LGIC_ECD_HisCl	51..235	CDD:349793	55/187 (29%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
gabra6	XP_031754593.1	LIC	12..443	CDD:455710	136/462 (29%)
		LGIC_ECD	42..239	CDD:475126	59/199 (30%)