Protein Alignment ort and gabra2a

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_009305482.1
• Gene: gabra2a / 100150704
• ZFINID: ZDB-GENE-141216-16
• Length: 451
• Species: Danio rerio
• Alignment Length: 488
• Identity: 139/488 - (28%)
• Similarity: 221/488 - (45%)
• Gaps: 70/488 - (14%)

  Fly     2 VFQIIILVICTICMKHYAKGE--FQQSLAI-TDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMG 63
            :..:.:||:...|.:....|.  |:.::.: |.||...:..||....|....:.|.|...:.|..
Zfish    12 LIHLFLLVLWRACSEAEVSGSDAFKNNITLFTRILDRLLDGYDNRLRPGLGDRVTEVKTDIYVTS 76

  Fly    64 LDSIDENSMTYVADVFFAQTWKDHRLRL--PENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQ 126
            ...:.:..|.|..||||.|.|.|.||:.  |.|:.:...|:    ...:|.||:||.|.|.....
Zfish    77 FGPVSDTDMEYTVDVFFRQRWTDERLKFHGPMNILRLNNLM----ASKIWTPDTFFHNGKKSVAH 137

  Fly   127 TMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTT 191
            .||:||..:.:.::.|:||.::||::..|.|:...:|.|...|.|:..|.::|..::.:.|....
Zfish   138 NMTMPNKLLRIMENGTLLYTMRLTVQAECPMHLEDFPMDFHSCPLKFGSYAYTLTEVTYVWTRNA 202

  Fly   192 PLVVD---ENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIM 253
            .|.|:   :...|.|..|:.......|...|||.:|.:...|.|||::.|:|..||:|..|.||:
Zfish   203 TLSVEVAPDGSRLNQYDLMGQTVGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVIL 267

  Fly   254 SWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYC 318
            |.||||:..|:.|||...|||::||::|....:::|||.|:|..|:|.|::||..|||.||:|:.
Zfish   268 SQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 332

  Fly   319 LINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIF 383
            .:|....     :..|:..|.:..| .|||         .|...|..|..:.:|:.
Zfish   333 TVNYFTK-----RGWAWDGKSIVND-KKKE---------TSVMKKNNAYAVAVANY--------- 373

  Fly   384 DEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPA 448
                                    .|.|.:..:    .||::      :.|.|||...:|.....
Zfish   374 ------------------------APHIAKDSA----LPTVS------KSATPEPSKAQPVAKET 404

  Fly   449 QERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            ::.......|||.||::||.||.|.|.:||..:
Zfish   405 KKTFNSVSKIDRMSRIIFPVLFGSFNLVYWATY 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	133/454 (29%)
		LGIC_ECD_HisCl	51..235	CDD:349793	55/188 (29%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
gabra2a	XP_009305482.1	LIC	17..437	CDD:455710	139/481 (29%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	58/205 (28%)
		Cys-loop	166..180	CDD:349836	4/13 (31%)