Protein Alignment nec and SERPINB7

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_003775.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 114/399 - (28%)
• Similarity: 180/399 - (45%)
• Gaps: 66/399 - (16%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALI-YGASDGKTFRELQKA---------GEFSKNAM 164
            |...||:|:..:|...||.||..|:.|.|||: .||.| .:..::.|.         |..|.:..
Human    11 FCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQD-DSLSQIDKLLHVNTASGYGNSSNSQS 74

  Fly   165 AVAQDFESVI-----KYKKHLEGADLTL-----ATKVYYNRELGGVNHSYDEYAKFYFSAGTEAV 219
            .:....:.|.     .:|.:    ||::     |.|||      |.:..|.|.|:..:.|..|.|
Human    75 GLQSQLKRVFSDINASHKDY----DLSIVNGLFAEKVY------GFHKDYIECAEKLYDAKVERV 129

  Fly   220 DMQN-AKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYD 283
            |..| .:||...||.||.:.|..||::::....:......:|||||||:|:|:..|...:|....
Human   130 DFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCH 194

  Fly   284 FQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRP 348
            |:........||||..:..:.|:.:.:.....|||.| :...:|.:||                |
Human   195 FKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLL----------------P 242

  Fly   349 EFDLNRVAHRLRRQS--------------VAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVT 399
            |.||:.:.::|..|:              |.|..|:|:.|...:|.:.|:.||:..:|..:....
Human   243 ENDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADL 307

  Fly   400 KLMDQPVR--VSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVRTPASV 462
            ..:....|  :|:::.|:||.|.|.||||:||:.:..|...| |:.|.|.|:.||:|.:|....:
Human   308 SGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQL-PQSTLFRADHPFLFVIRKDDII 371

  Fly   463 LFIGHVEYP 471
            ||.|.|..|
Human   372 LFSGKVSCP 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	113/397 (28%)
SERPINB7	NP_003775.1	serpinB7_megsin	1..380	CDD:381032	113/397 (28%)