DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nec and Serpine3

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	85/368 - (23%)
Similarity:	155/368 - (42%)	Gaps:	38/368 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESV- 173
            |:..|::......:..|.|.||.||...|.::..|:.|.|..:|.:|..::.....|.:...:|
  Rat    35 FALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEALGYTVQDPRVREFLHTVY 99

  Fly   174 IKYKKHLEGADLTLATKVYYNRELG-GVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMD 237
            |......:|..:.||..::  .:.| .::..:.|....:.::..|..|.       ::.|...|:
  Rat   100 ITLHNSSQGIGMELACTLF--MQTGTSLSPCFVEQVSRWANSSLELADF-------SEPNTTTME 155

  Fly   238 TTRNKIRDLVTPTDVDP--------QTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKV 294
            .::...|.........|        .||..:|:.:.||..|:..|:::...|..|...:|.:.:|
  Rat   156 ASKGTTRPSTGEGPGSPLWGRAGALSTQLSIVSTMTFQSSWQQRFSSVALQPLPFTCAHGLVLQV 220

  Fly   295 AMMFNDDVYGLAELPELG---ATALELAYKDSATSMLILLPNET-TGLGKMLQQLSRPEFDLNRV 355
            ..|.........:..:..   ...|||.|.....|:|::||.:. |.|..:...|:.      ||
  Rat   221 PAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQDKGTPLDHIEPHLTA------RV 279

  Fly   356 AH----RLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD--QPVRVSKILQK 414
            .|    ||:|..:.|.||:|:.:.:.|:...|::.|:..:|.|.....|.:.  ....||::..|
  Rat   280 IHLWTTRLKRARMDVFLPRFRIQNQFDLKSILRSWGITDLFDPLKANLKGISGRDGFYVSEVTHK 344

  Fly   415 AYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVR 457
            |.:.:.|.||::.||:....:..|..|   .|.|:|||:|.:|
  Rat   345 AKMELSEEGTKSCAATAVLLLRRSRTP---AFKADRPFIFLLR 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	85/368 (23%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	85/368 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110