Protein Alignment nec and SERPINA7

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 100/395 - (25%)
• Similarity: 178/395 - (45%)
• Gaps: 52/395 - (13%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKN---AMAVAQDFE 171
            |:..|::........:|:.|||.|:.|.|.::...:...|..|:.:...|:..   .:.:...|:
Human    49 FAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQ 113

  Fly   172 SVIKY----KKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTE--AVDMQNAKDTAAK 230
            .:|..    ||.||   |.:...::..:.|..:....::....|   .||  :.|..|......:
Human   114 HLICSLNFPKKELE---LQIGNALFIGKHLKPLAKFLNDVKTLY---ETEVFSTDFSNISAAKQE 172

  Fly   231 INAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEF---ATMDTSPYDFQHTNGRIS 292
            ||:.|...|:.|:..|:  .|:.|.|..:|||.::|:.:|.:.|   .|.|:|.:....|.  ..
Human   173 INSHVEMQTKGKVVGLI--QDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTT--TV 233

  Fly   293 KVAMMFN-DDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQ-QLSRPEFDLNRV 355
            :|.||.. :..|.|.:: ||..|.|::.|..:|.: |.:||.|    |:|.. :.:.....|.:.
Human   234 QVPMMHQMEQYYHLVDM-ELNCTVLQMDYSKNALA-LFVLPKE----GQMESVEAAMSSKTLKKW 292

  Fly   356 AHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVT--------KLMDQP---VRVS 409
            ...|::..|.:.:|||......|:...|..:|:...::.|:..:        ||.::|   |..:
Human   293 NRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNRPAGFVLPT 357

  Fly   410 KILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFV-----ANRPFVFAV--RTPASVLFIGH 467
            :...||.:::||.||||:|...   |.||..|:.| |:     .:|.|:..:  |:..|:||:|.
Human   358 QAAHKAVLHIGEKGTEAAAVPE---VELSDQPENT-FLHPIIQIDRSFMLLILERSTRSILFLGK 418

  Fly   468 VEYPT 472
            |..||
Human   419 VVNPT 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	97/389 (25%)
SERPINA7	XP_006724746.1	alpha-1-antitrypsin_like	46..419	CDD:239011	97/389 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010