DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nec and Serpina1f

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_080963.2	Gene:	Serpina1f / 68348	MGIID:	1915598	Length:	411	Species:	Mus musculus

Alignment Length:	409	Identity:	87/409 - (21%)
Similarity:	177/409 - (43%)	Gaps:	37/409 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 VVAVDLTKREPVTPPPNRPP----PVFSYMDRFSSELFKEIIKSQSQQNVVFSPFSVHALLALIY 142
            ::.:..||.|.:...|:..|    .|...:...|..|||::.:.....|::|||..|.|.::::.
Mouse    19 LLLITKTKHEKLYEDPSIDPFQCRKVALTICNVSITLFKKMAQLSGNGNILFSPIRVIAAISMLS 83

  Fly   143 GASDGKTFRELQKAGEFSKNAMAVAQDFESVIKYKKHL-----EGADLTLATKVYYNRELGGVNH 202
            ..|:|...:.:.:...|:|..:..| :......|..|.     |.:.|...:.|:.:::|..|:
Mouse    84 LGSNGNLSKHILETLRFNKTGLPEA-EIHKCFWYLLHSIHQTEEPSSLQTGSSVFIHQDLTSVD- 146

  Fly   203 SYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQ 267
            .:.:..|..:.:...:::..::.....:||.:||:.::.:|.::|  .:::..|...:||.:.:.
Mouse   147 KFVKGVKDLYHSDMISINFTDSSQAKTQINNYVMEKSQKEIVNIV--KNLESDTFLAVVNYIIWN 209

  Fly   268 GRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLP 332
            .:.:..|........|:....|...||.|:.|..::.|..:.:|.:|.|.|.......:...::|
Mouse   210 AKLDSNFGCRSVKVKDYHLGYGMTIKVPMIHNMAMHYLFRVEDLSSTVLMLTLLTGNFATYFIIP 274

  Fly   333 NETTGLGKML---QQLSRPEFDLNRVAHRLRRQ----SVAVRLPKFQFEFEQDMTEPLKNLGVHQ 390
            :.    |||.   |.|:.|.|      .|:|||    .|.:.:|:.......|:...:..||:..
Mouse   275 DP----GKMQKVEQSLTYPHF------RRMRRQLLTRLVDLEIPELSLSETHDLESMMSLLGITY 329

  Fly   391 MFTPNSQVTKLMDQPVRVSKILQKAYINVGEAGTEASAAS-YAKFVPLSLPPKPTEFVANRPFVF 454
            :|...:..:.:.|...:..|::.||.:.:.|.|::.|..| :.|.....:    .....||||:.
Mouse   330 VFNSGTNSSDMNDTLQKSFKVVSKAVLTIDEKGSKPSTNSCFKKLGSTDM----GRMQLNRPFLI 390

  Fly   455 AVR--TPASVLFIGHVEYP 471
            .::  |....||:|.|..|
Mouse   391 FIQDHTNDVPLFLGRVVNP 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	79/374 (21%)
Serpina1f	NP_080963.2	Serpin	48..409	CDD:278507	80/378 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7631
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.050