DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nec and Serpina5

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001231668.1	Gene:	Serpina5 / 65051	RGDID:	619817	Length:	442	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	93/380 - (24%)
Similarity:	176/380 - (46%)	Gaps:	38/380 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174
            |:..|::.:......|||.|||.||...|.::...|..||     ||.......:::.|..|.::
  Rat    83 FAFRLYRALASEAPGQNVFFSPMSVSMSLGMLSLGSGLKT-----KAQILEGLGLSLQQGQEDML 142

  Fly   175 ---------KYKKHLEGADLTLATKVYYNRELGGVNHSYDEY---AKFYFSAGTEAVDMQNAKDT 227
                     ::.:..:|..|:|.:.::.:..:    |..|.:   .|..:.:...:.:..|.:..
  Rat   143 HKGFQQLLQQFSQPSDGLQLSLGSALFTDPAV----HIRDHFLSAMKTLYMSDMFSTNFGNPESA 203

  Fly   228 AAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRIS 292
            ..:||.:|...|..||.||:  .|:|.....::||.::|:.:|:..|::.:|...|:..|..:..
  Rat   204 KKQINDYVAKKTNGKIVDLI--KDLDSTHVMVVVNYIFFKAKWQTAFSSTNTHKMDYHVTPKKTI 266

  Fly   293 KVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAH 357
            :|.||..:|:|.......:..|.:.:.|:.: |..|.:||:|    |||    .|.|..|:....
  Rat   267 QVPMMNREDIYSYILDQNISCTVVGIPYQGN-TFALFILPSE----GKM----KRVEDGLDERTL 322

  Fly   358 R-----LRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQP-VRVSKILQKAY 416
            |     ..::.:.:.||||..|....:.:.|..||:..:||.::.::.|.|.. :::|:::.|:.
  Rat   323 RNWLKMFTKRQLDLYLPKFSIEGTYKLEKILPKLGIQDIFTTHADLSGLTDHTNIKLSEMVHKSM 387

  Fly   417 INVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVRTPASVLFIGHVEYP 471
            :.|.|:||.|:|::...|...|..|...:....|||:..:....::.|||.|..|
  Rat   388 VEVDESGTTAAASTGILFTLRSARPSSLKVEFTRPFLVVIMDGTNLYFIGKVIQP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	91/375 (24%)
Serpina5	NP_001231668.1	alpha-1-antitrypsin_like	81..439	CDD:239011	91/375 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010