DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nec and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	401	Identity:	108/401 - (26%)
Similarity:	187/401 - (46%)	Gaps:	34/401 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 REPVTPPP--NRPPPVFSYMDRFSSELFKEIIKSQSQQ--NVVFSPFSVHALLALIYGASDGKTF 150
            :|.:..||  .:.|.:.:..:.|:..|:|.:|:|...|  |:.||||||...|:.:...:.|.|.
Zfish    21 QETLQQPPISAKLPSLINMNNDFAFHLYKRVIESPDYQSKNIFFSPFSVSIALSELSLGAGGDTK 85

  Fly   151 REL-----QKAGEFSKNAMAVAQDFESVIKYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKF 210
            ::|     ..:..||...|  .|.|.|:::...:..|.|:.:.|.:|.:......:...::..:|
Zfish    86 QQLLSGIGYNSTTFSTEEM--HQLFHSLLEDIGNRTGVDIDVGTALYASDRFKPHSKFLEDMKEF 148

  Fly   211 YFSAGTEAVDMQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFA 275
            |.|.|. .||.: .|:|..:||.:....|:.|....|  .|::..|...|:..:||:|:|:..|.
Zfish   149 YHSDGF-TVDFR-VKETVDQINNYAKKKTQGKFNQAV--DDLEEDTLMFLLTYIYFKGKWDKPFK 209

  Fly   276 TMDTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPN---ETTG 337
            ...|....|...:.....|.||...:...:....||....|.|.|||| .||.:.:|:   |...
Zfish   210 PEKTRESTFHIDDKTTVPVQMMHQYERLKVFYDAELSTKVLCLDYKDS-FSMFLAVPDDKMEHKN 273

  Fly   338 LGKMLQQLSRPEFDLNRVAHRLRR----QSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQV 398
            :..:...:||..|:      :.||    ::|.:.:||...:....:.:.||.:|:..||:..:..
Zfish   274 IKDLEMTVSRQHFE------KWRRSAFKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKANF 332

  Fly   399 TKLMDQPVRVSKILQKAYINVGEAGTEASAASYAKF-VPLSLPPKPTEFVANRPFVFAV--RTPA 460
            |.:.::.:.|||:|.||.:::.|.||.|:|.:.... |.|..|....:|  ||||:..:  :|..
Zfish   333 TGVSEEKIFVSKVLHKATLDIDEQGTTAAAVTGVSMRVRLHNPLSILKF--NRPFMVFITDQTND 395

  Fly   461 SVLFIGHVEYP 471
            ::||.|.|..|
Zfish   396 NILFFGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	102/376 (27%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	102/378 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020