Protein Alignment nec and SERPINB13

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 112/395 - (28%)
• Similarity: 179/395 - (45%)
• Gaps: 36/395 - (9%)

  Fly   109 RFSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKA--GEFSKNAMAVAQDFE 171
            |...:|||| :|..:..|:.|||..:...:.::...:.|.|..:|::.  .|....:..:..:.:
Human    10 RLGFDLFKE-LKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEK 73

  Fly   172 SVIKYK---KHLEGAD---------LTLATKVYYNRELGGVN-----------HSYDEYAKFYFS 213
            .|::.|   |.:|..:         ||..:|:..:.||...|           ..|.:|.:.|:.
Human    74 EVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYH 138

  Fly   214 AGTEAVDMQNAKD-TAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATM 277
            |..|.||..||.| :..|||:||...|..||:||.....:...|:.:|||.|||:|:|:.||...
Human   139 ASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKE 203

  Fly   278 DTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKML 342
            :|....|.........|.||.....:....|.:|.|..|.:.||::..||.:||||:..||.|::
Human   204 NTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKII 268

  Fly   343 QQLSRPE--FDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD-- 403
            .::| ||  .:.....| :..:.|.:.||:|:.|...|:...|..:|:...|:.:......|.
Human   269 DKIS-PEKLVEWTSPGH-MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSG 331

  Fly   404 QPVRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIG 466
            ..:...|.|..:::.|.|.||||:||:...|...|.|...... .|.||:|.:|  ...|:||.|
Human   332 SGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH-CNHPFLFFIRHNESNSILFFG 395

  Fly   467 HVEYP 471
            ....|
Human   396 RFSSP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	111/390 (28%)
SERPINB13	NP_001294852.1	SERPIN	4..400	CDD:294093	111/393 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830