Protein Alignment nec and SERPINB6

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 114/378 - (30%)
• Similarity: 194/378 - (51%)
• Gaps: 28/378 - (7%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMA--VAQDFES 172
            |:..|.|.:.|..| :||.|||.|:...||::|..:.|.|..::.:...|:|:...  :.|.|:|
Human    89 FALNLLKTLGKDNS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQS 152

  Fly   173 VIKYKKHLEGAD--LTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAK-INAW 234
            ::. :.:..|..  |.:|.:::..:....::...|...||| .|..|.:|..:|.:.:.| ||.|
Human   153 LLT-EVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFY-QAEMEELDFISAVEKSRKHINTW 215

  Fly   235 VMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFN 299
            |.:.|..||.:|::|..|||.|:.:|||||||:|.|:.:|...:|....|:.:......|.|||.
Human   216 VAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFK 280

  Fly   300 DDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF-DLNRVAHRLRRQS 363
            ...:....:.|:....|.|.|.....:|:|:||:|||.|..:.::|:..:| :..|: ..:..:.
Human   281 QSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRL-DMMDEEE 344

  Fly   364 VAVRLPKFQFEFEQDMTEPLKNLGVHQMF-TPNSQVTKLMDQPVRVSKILQKAYINVGEAGTEAS 427
            |.|.||:|:.|...||...|:|||:...| ...:..:.:....:.:||::.|:::.|.|.||||:
Human   345 VEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAA 409

  Fly   428 AAS-------YAKFVPLSLPPKPTEFVANRPFVFAVRTPAS--VLFIGHVEYP 471
            ||:       .|:|||        .|.|:.||:|.::...:  :||.|....|
Human   410 AATAAIMMMRCARFVP--------RFCADHPFLFFIQHSKTNGILFCGRFSSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	113/373 (30%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	113/376 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730