Protein Alignment nec and SERPINF1

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001316832.1
• Gene: SERPINF1 / 5176
• HGNCID: 8824
• Length: 418
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 96/437 - (21%)
• Similarity: 182/437 - (41%)
• Gaps: 96/437 - (21%)

  Fly    90 REPVTPPPNRPP-------------PVF--------SYMDRFSSELFKEIIKSQSQQNVVFSPFS 133
            :.|.:||....|             |.|        :.:..|..:|::....:....||:.||.|
Human    20 QNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLS 84

  Fly   134 V-HALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVIKYKKHLEGA-----DLTLATKVY 192
            | .||.||..|| :.:|...:.:|..:.   :..:.|....  ||:.|:..     :|..|:::.
Human    85 VATALSALSLGA-EQRTESIIHRALYYD---LISSPDIHGT--YKELLDTVTAPQKNLKSASRIV 143

  Fly   193 YNREL-------GGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMDTTRNKIRDLVTPT 250
            :.::|       ..:..||....:..  .|...:|:|       :||.||....:.|:..  :..
Human   144 FEKKLRIKSSFVAPLEKSYGTRPRVL--TGNPRLDLQ-------EINNWVQAQMKGKLAR--STK 197

  Fly   251 DVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDV---YGL------- 305
            ::..:...||:...:|:|:|..:|.:..||..||.....|..:|.||.:...   |||
Human   198 EIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCK 262

  Fly   306 -AELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF--DLNRVAHRLRRQSVAVR 367
             |:||..|           :.|::..||.:.|....::::....||  |::|   .|:.....:.
Human   263 IAQLPLTG-----------SMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDR---ELKTVQAVLT 313

  Fly   368 LPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVRVSKILQKAYINVGE--AGTEASAAS 430
            :||.:..:|.::|:.|:.:.:..:| .:...:|:..:|::::::..:|.....|  |||..|.
Human   314 VPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSP-- 375

  Fly   431 YAKFVPLSLPPK----PTEFVANRPFVFAVR--TPASVLFIGHVEYP 471
                   .|.|.    |.::..|:||:|.:|  ...::||||.:..|
Human   376 -------GLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	89/393 (23%)
SERPINF1	NP_001316832.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		4/18 (22%)
		PEDF	40..415	CDD:239007	91/415 (22%)
		O-glycosylated at one site	371..383		4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010