Protein Alignment nec and SERPINA5

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 112/449 - (24%)
• Similarity: 205/449 - (45%)
• Gaps: 60/449 - (13%)

  Fly    39 QLQLQQQLLLQQQQ----HQRNPRPELGLRSLPGNPWTQNNQEAISDVVAVDLTKREPVTPPPNR 99
            ||.|...|:|...|    |:.:|| |:..|                   ..||.....|.|...|
Human     2 QLFLLLCLVLLSPQGASLHRHHPR-EMKKR-------------------VEDLHVGATVAPSSRR 46

  Fly   100 PPPVFSYMDRFSSELFKEIIKSQSQQNVVFSPFSVH---ALLALIYGASDGKTFRE-----LQKA 156
            .         |:.:|::.:..:...|::.|||.|:.   |:|:|..|:|......|     |||:
Human    47 D---------FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS 102

  Fly   157 GEFSKNAMAVAQDFESVI-KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVD 220
            .|     ..:.:.|:.:: :..:..:|..|:|...::.:..: .:..::....|..:.|.|...:
Human   103 SE-----KELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVV-DLQDTFVSAMKTLYLADTFPTN 161

  Fly   221 MQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQ 285
            .:::.....:||.:|...|:.||.||:  .::|.....::||.::|:.:||..|....|...||.
Human   162 FRDSAGAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224

  Fly   286 HTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSR--P 348
            .|:..:.:|.||..:|.|.......|....:.:.|:.:||: |.:||:|    ||| ||:..  .
Human   225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATA-LFILPSE----GKM-QQVENGLS 283

  Fly   349 EFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQP-VRVSKIL 412
            |..|.:.....:::.:.:.||||..|....:.:.|.:||:..:||.::.::.:.:.. ::||:::
Human   284 EKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMV 348

  Fly   413 QKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVRTPASVLFIGHVEYP 471
            .||.:.|.|:||.|:||:...|...|........|.||||:..: ...::||:|.|..|
Human   349 HKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI-VDNNILFLGKVNRP 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	94/371 (25%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	95/382 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010