Protein Alignment nec and SERPINB2

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 107/410 - (26%)
• Similarity: 198/410 - (48%)
• Gaps: 53/410 - (12%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSK------------- 161
            |:..|||.:.|:...||:..||:|:.:.:|::|..|.|.|..::.|..:|::
Human    11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPEN 75

  Fly   162 ----------------NAMAVAQDFESVIKYKKHLEGADLTLATKVY----YNRELGGVNHSY-D 205
                            :|:..||..:.:....:.|..| :..:|..|    .|:..|..:.|: :
Human    76 FTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSA-INASTGNYLLESVNKLFGEKSASFRE 139

  Fly   206 EYAKF---YFSAGTEAVD-MQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYF 266
            ||.:.   |:|:..:||| ::.|::...|||:||...|:.||.:|:....||..|:.:|||||||
Human   140 EYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYF 204

  Fly   267 QGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILL 331
            :|:|:..|.......|.|:..:.:.:.|.||:..:...:..:.:|.|..|||.|... .||.:||
Human   205 KGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGD-VSMFLLL 268

  Fly   332 PNE----TTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMF 392
            |:|    :|||..:..:::..:.:......::....|.|.:|:|:.|...::...|:::|:...|
Human   269 PDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAF 333

  Fly   393 TPN----SQVTKLMDQPVRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFV 453
            ...    |.:::..|  :.:|::..:|.::|.|.||||:|.:.......:....| :|||:.||:
Human   334 NKGRANFSGMSERND--LFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGP-QFVADHPFL 395

  Fly   454 FAV--RTPASVLFIGHVEYP 471
            |.:  :....:||.|....|
Human   396 FLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	106/405 (26%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	106/408 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930