Protein Alignment nec and SERPINC1

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 97/418 - (23%)
• Similarity: 186/418 - (44%)
• Gaps: 59/418 - (14%)

  Fly   109 RFSSELFKEIIKSQS-QQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFES 172
            ||::..::.:..|:: ..|:..||.|:....|:....:...|.::|.:..:|...:...:.....
Human    89 RFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHF 153

  Fly   173 VIK------YKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDM-QNAKDTAAK 230
            ...      |:|..:.:.|..|.:::.::.| ..|.:|.:.::..:.|..:.:|. :||:.:.|.
Human   154 FFAKLNCRLYRKANKSSKLVSANRLFGDKSL-TFNETYQDISELVYGAKLQPLDFKENAEQSRAA 217

  Fly   231 INAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYF----------------------------- 266
            ||.||.:.|..:|.|::....::..|..:|||.:||
Human   218 INKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDR 282

  Fly   267 ------------QGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELA 319
                        ||.|:.:|:..:|....|...:|.....:||:.:..:....:.| |...|||.
Human   283 SPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELP 346

  Fly   320 YKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLK 384
            :|....:|:::||.....|.|:.::|: ||. |......|....:.|.:|:|:.|....:.|.|:
Human   347 FKGDDITMVLILPKPEKSLAKVEKELT-PEV-LQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQ 409

  Fly   385 NLGVHQMFTP-NSQVTKLMDQ---PVRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTE 445
            ::|:..:|:| .|::..::.:   .:.||....||::.|.|.|:||:|::.......||.|....
Human   410 DMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVT 474

  Fly   446 FVANRPF-VFAVRTPA-SVLFIGHVEYP 471
            |.||||| ||....|. :::|:|.|..|
Human   475 FKANRPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	95/413 (23%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	97/418 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890