DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nec and LOC299282

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001376144.2	Gene:	LOC299282 / 299282	RGDID:	3745	Length:	413	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	104/376 - (27%)
Similarity:	187/376 - (49%)	Gaps:	29/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALI-YGASDGKTFRELQKAGEFSKNAMA---VAQDF 170
            |:..|:|::......:||||||.|:.|.|.:: .||.| .|..|:.:..:|:...:.   :.|.|
  Rat    52 FALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKD-STMEEILEGLKFNLTEITEEEIHQGF 115

  Fly   171 ESVIKYKKHLEG-ADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAW 234
            ..:::.....|. .::...:.::.::| ..:...:.|..:..:.|.....|.:...:....||.:
  Rat   116 GHLLQRLSQPEDQVEINTGSALFIDKE-QPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDY 179

  Fly   235 VMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFN 299
            |.:.|:.||.:|.  :|::.:|..:|||.:.|:|:|:..|...||...:|.....|..||.||..
  Rat   180 VSNQTQGKIAELF--SDLEERTSMVLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKI 242

  Fly   300 DDV---YGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLS--RPEFDLNRVAHRL 359
            .:|   |...|  ||..:.|||.|..:| |.|.:||::    |||.|..|  :|| .|.:....|
  Rat   243 KEVTTPYVRDE--ELSCSVLELKYTGNA-SALFILPDQ----GKMQQVESSLQPE-TLKKWKDSL 299

  Fly   360 RRQSV-AVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLM-DQPVRVSKILQKAYINVGEA 422
            ..:.: .:|:|||....:..:.|.|..||:.::|:..:.::::. .:.:.||:::.||.::|.|.
  Rat   300 IPRIINDLRMPKFSISTDYSLKEVLPELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDET 364

  Fly   423 GTEASAASYAKFVPLSLPPKPTEFVANRPFVFAV--RTPASVLFIGHVEYP 471
            ||||:||:....| :...|:...|  ||||:..:  ....|:||:..:..|
  Rat   365 GTEATAATGVATV-IRRQPRTLNF--NRPFMVVITDMDSQSILFVAKITNP 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	103/371 (28%)
LOC299282	NP_001376144.2	serpinA3_A1AC	36..413	CDD:381019	104/376 (28%)
LOC299282	NP_001376144.2	RCL	365..389		9/26 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010