Protein Alignment nec and Serpine2

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_062070.1
• Gene: Serpine2 / 29366
• RGDID: 3748
• Length: 397
• Species: Rattus norvegicus
• Alignment Length: 392
• Identity: 122/392 - (31%)
• Similarity: 197/392 - (50%)
• Gaps: 35/392 - (8%)

  Fly   103 VFSYMDRFSSE---------LFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGE 158
            |:|.::..|.|         :|.:|||||..:|||.||..:.::|.::...:||:|.::|.....
  Rat    18 VYSQLNSLSLEELGSDTGIQVFNQIIKSQPHENVVISPHGIASILGMLQLGADGRTKKQLSTVMR 82

  Fly   159 FSKNAMA-VAQDFESVIKYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQ 222
            ::.|.:. |.:.....|..||:   .|:.......:.|....|...:....|..|....::|:.|
  Rat    83 YNVNGVGKVLKKINKAIVSKKN---KDIVTVANAVFVRNGFKVEVPFAARNKEVFQCEVQSVNFQ 144

  Fly   223 NAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQ-TQALLVNAVYFQGRWEHEFATMDTSPYDFQH 286
            :.......||.||.:.||..|.:|::|..:|.. |:.:|||||||:|.|:..|...:|....|..
  Rat   145 DPASACDAINFWVKNETRGMIDNLLSPNLIDSALTKLVLVNAVYFKGLWKSRFQPENTKKRTFVA 209

  Fly   287 TNGRISKVAMMFNDDVY--GLAELPE-LGATALELAYKDSATSMLILLPNE-TTGLGKMLQQLSR 347
            .:|:..:|.|:....|:  |..:.|. |....:||.|...:.||||.||.| :|.|..::..:|.
  Rat   210 GDGKSYQVPMLAQLSVFRSGSTKTPNGLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHIST 274

  Fly   348 PEFD--LNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPN----SQVTKLMDQPV 406
            ...:  :|.:..: |.|.|   ||||....:.|:.||||.||:.:||.|:    :::|:  .:.:
  Rat   275 KTINSWMNTMVPK-RMQLV---LPKFTAVAQTDLKEPLKALGITEMFEPSKANFAKITR--SESL 333

  Fly   407 RVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVE 469
            .||.|||||.|.|.|.||:|:..:.|..:..|.||   .|:.:|||:|.:|  ...::||:|.|.
  Rat   334 HVSHILQKAKIEVSEDGTKAAVVTTAILIARSSPP---WFIVDRPFLFCIRHNPTGAILFLGQVN 395

  Fly   470 YP 471
            .|
  Rat   396 KP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	120/388 (31%)
Serpine2	NP_062070.1	serpinE2_GDN	21..395	CDD:381039	118/385 (31%)