Protein Alignment nec and Serpinb1b

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 375
• Identity: 123/375 - (32%)
• Similarity: 187/375 - (49%)
• Gaps: 16/375 - (4%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174
            |:.|||..:.:|....|:.|||||:.:.||:::..:.|.|..:|.|...|. :...:...|:|:.
Mouse    11 FTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHFD-SVEDIHSCFQSLT 74

  Fly   175 KYKKHLEGAD--LTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAK-INAWVM 236
            .....| ||.  |.||.::|..:....:........|.| ||...|||.|:|.:.|.| ||.||.
Mouse    75 AEVSKL-GASHTLKLANRLYGEKTYNFLPEFLASTQKMY-SADLAAVDFQHASEDARKEINQWVK 137

  Fly   237 DTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDD 301
            ..|..||.:|:....||..|:.:||||:||:|.||.:|.|.:|....|:........|.||:...
Mouse   138 GQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMMYQKK 202

  Fly   302 VYGLAELPELGATALELAYKDSATSMLILLP----NETTGLGKMLQQLSRPEFDLNRVAHRLRRQ 362
            .:....:.:|....||:.|:....||:||||    :|:|||.|:.:||:..:.........||..
Mouse   203 KFPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQLTLGKLHEWTKHENLRNI 267

  Fly   363 SVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLM--DQPVRVSKILQKAYINVGEAGTE 425
            .|.|:||:|:.|....:...|..|||..:|:........|  .:.:.||||:.|::::|.|.|||
Mouse   268 DVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGMSGSRDLFVSKIVHKSFVDVNEQGTE 332

  Fly   426 ASAASYAKF-VPLSLPPKPTE-FVANRPFVFAVR--TPASVLFIGHVEYP 471
            |:||:.... |.....|.|.| |..:.||:|.:|  ..|:::|.|.|..|
Mouse   333 AAAATGGIIQVLCEKMPTPQEVFTVDHPFLFFIRHNPTANMIFFGRVCSP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	121/370 (33%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	122/373 (33%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		10/29 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830