Protein Alignment nec and SERPINA11

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 103/410 - (25%)
• Similarity: 183/410 - (44%)
• Gaps: 56/410 - (13%)

  Fly    95 PPPNR-----PPPVF----SYMDRFSSELFKEIIKSQSQQNVVFSPFSVHALLALI-YGASDGKT 149
            |.|.|     |.|.:    ..:..|:..|:|| :.:.:..|:.|||.|:...|||: .||....:
Human    33 PQPPRHQLSEPAPAYHRITPTITNFALRLYKE-LAADAPGNIFFSPVSISTTLALLSLGAQANTS 96

  Fly   150 FRELQKAG-EFSKNAMA-VAQDFESVIKYKKHL-----EGADLTLATKVYYNRELGGVNHSYDE- 206
            ...|:..| ..::...| :.|.|.|::    |.     ...:|.:...::.::.|....|..|.
Human    97 ALILEGLGFNLTETPEADIHQGFRSLL----HTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSI 157

  Fly   207 ---YAKFYFSAG-TEAVDMQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQ 267
               |..|.|||. |::|      .|..:||.::...|..::.|.:.....|  |..:|.|.::|:
Human   158 KELYGAFAFSANFTDSV------TTGRQINDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFK 214

  Fly   268 GRWEHEFATMDTSPYDFQHTNGRIS-KVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILL 331
            .:|:|.|:...|...:....:.|.| :|.||...:::......:|..|.|::.|:.:|.::|: |
Human   215 AKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-L 278

  Fly   332 PNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNS 396
            |:  .|..|.::...:|: .|.:....|....:.:.||:|......::.:.|..:|:..:....:
Human   279 PD--PGKMKQVEAALQPQ-TLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEA 340

  Fly   397 QVTKLMDQPVR-VSKILQKAYINVGEAGTEASAASYAKFVPLSLPPK-------PTEFVANRPFV 453
            ..:.:..|..: :||:..||.:::.|.||||.|||..    ||.||.       ...|  ||||:
Human   341 DFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGL----LSQPPSLNTMSDPHAHF--NRPFL 399

  Fly   454 FAV--RTPASVLFIGHVEYP 471
            ..:  .|..|:||:|.|..|
Human   400 LLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	96/383 (25%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	96/385 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010