DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nec and Serpinb9

DIOPT Version :9

Sequence 1:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_033282.1	Gene:	Serpinb9 / 20723	MGIID:	106603	Length:	374	Species:	Mus musculus

Alignment Length:	369	Identity:	106/369 - (28%)
Similarity:	179/369 - (48%)	Gaps:	12/369 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174
            |:..|.|.:.:|...:||.:||.|:.:.||::...:.|:|..::.:|...:|.. .:.|.|:.::
Mouse    11 FAIHLLKMLCQSNPSKNVCYSPASISSALAMVLLGAKGQTAVQISQALGLNKEE-GIHQGFQLLL 74

  Fly   175 -KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMDT 238
             |..|......|.:|.:::.::....:....:....||.|...:....:.|:.:...||.||...
Mouse    75 RKLNKPDRKYSLRVANRLFADKTCEVLQTFKESSLHFYDSEMEQLSFAEEAEVSRQHINTWVSKQ 139

  Fly   239 TRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVY 303
            |..||.:|::...||.:|:.:|:||:||:|:|...|....|....|:........|.||..:|.|
Mouse   140 TEGKIPELLSGGSVDSETRLVLINALYFKGKWHQPFNKEYTMDMPFKINKDEKRPVQMMCREDTY 204

  Fly   304 GLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVRL 368
            .||.:.|:.|..|.:.|:....|:::|||:|...|.|:...|:..:......|..::...|.|.|
Mouse   205 NLAYVKEVQAQVLVMPYEGMELSLVVLLPDEGVDLSKVENNLTFEKLTAWMEADFMKSTDVEVFL 269

  Fly   369 PKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVR---VSKILQKAYINVGEAGTEASAAS 430
            |||:.:.:.||....:.|||..:|..:......| .|.|   |||.:.::.:.:.|.||||:|||
Mouse   270 PKFKLQEDYDMESLFQRLGVVDVFQEDKADLSGM-SPERNLCVSKFVHQSVVEINEEGTEAAAAS 333

  Fly   431 -YAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYP 471
             ..:|...|..|   .|.|:.||:|.:|  ...|:||.|....|
Mouse   334 AIIEFCCASSVP---TFCADHPFLFFIRHNKANSILFCGRFSSP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	105/364 (29%)
Serpinb9	NP_033282.1	serpin	1..374	CDD:393296	105/367 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930