Protein Alignment nec and Serpinb6a

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001157589.1
• Gene: Serpinb6a / 20719
• MGIID: 103123
• Length: 399
• Species: Mus musculus
• Alignment Length: 384
• Identity: 109/384 - (28%)
• Similarity: 186/384 - (48%)
• Gaps: 38/384 - (9%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSK----NAMAVAQDF 170
            |:..|.| |:...|.:||..||.|:.:.||:::..:.|.|..::.:|....|    ....|.|.|
Mouse    32 FALNLLK-ILGEDSSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGGDVHQGF 95

  Fly   171 ESVIKYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKF------YFSAGTEAVDMQNA-KDTA 228
            :|::. :.:..|....|.|.   ||..|  :.:.|..|.|      ::.|..|.:|.|.| :::.
Mouse    96 QSLLT-EVNKTGTQYLLRTA---NRLFG--DKTCDLLASFKDSCLKFYEAELEELDFQGATEESR 154

  Fly   229 AKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISK 293
            ..||.||...|.:||:::::|..|:..|..:||||:||:|.||.:|....|....|:.:......
Mouse   155 QHINTWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMPFKVSKNEEKP 219

  Fly   294 VAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF-DLNRVAH 357
            |.|||....:.:..:.|:....|.|.|..|..:|:|:||:|...|..:.::::..:| :..|: .
Mouse   220 VQMMFKKSTFKMTYIGEIFTKILLLPYVSSELNMIIMLPDEHVELSTVEKEVTYEKFIEWTRL-D 283

  Fly   358 RLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD-QPVRVSKILQKAYINVGE 421
            ::..:.|.|.||||:.|...:|.:.|..||:...|...:..:.:.. |.:.:||::.||::.|.|
Mouse   284 KMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAFGGRADFSGMSSKQGLFLSKVVHKAFVEVNE 348

  Fly   422 AGTEASAASYA-------KFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYP 471
            .||||:||:..       :|.|        .|.|:.||:|.:.  ....:||.|....|
Mouse   349 EGTEAAAATAGMMTVRCMRFTP--------RFCADHPFLFFIHHVKTNGILFCGRFSSP 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	108/382 (28%)
Serpinb6a	NP_001157589.1	serpinB6_CAP	22..399	CDD:381031	108/382 (28%)