Protein Alignment nec and Serpina12

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_620180.2
• Gene: Serpina12 / 191570
• RGDID: 708485
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 368
• Identity: 88/368 - (23%)
• Similarity: 181/368 - (49%)
• Gaps: 15/368 - (4%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSK-NAMAVAQDFESV 173
            |..:|.:.:..:..|.|:..||.|:....:::...:...|..|:::...|.: :...:...|..:
  Rat    55 FGFKLLQRLASNSRQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSDRDMHMGFHYL 119

  Fly   174 I-KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMD 237
            : |..:..:...:::...::.::.| .....:.:.||..:.|.....:.|:.::|...||.::..
  Rat   120 LQKLNRETQDVKMSIGNALFMDQRL-RPQQRFLKLAKNLYDADMILTNFQDLENTQKNINKYISR 183

  Fly   238 TTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDV 302
            .|.|:|.::|  .::||.|..||.|.:||||||::||....|...||....|:..||.|||...:
  Rat   184 KTHNRIENMV--KNIDPGTVMLLTNYIYFQGRWQYEFDPKQTKEEDFFIEEGKTVKVPMMFQRGM 246

  Fly   303 YGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVR 367
            |.:|...:|..|.||:.|:.:.|:..: ||:  :|..::|:|..:.:. ..:....|.::.|.|.
  Rat   247 YDMAYDSQLSCTILEMPYRRNITATFV-LPD--SGKLRLLEQGLQADI-FAKWKSLLSKRVVDVW 307

  Fly   368 LPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD-QPVRVSKILQKAYINVGEAGTEASAASY 431
            :|:.......:|.:.|..||:.::|..:..:|::.. :.::|.:.:.||.:.:.|.|||.:|.|.
  Rat   308 VPRLHISATYNMKKVLSRLGISKIFEEHGDLTRISSHRSLKVGEAVHKAELRMNEKGTEGAAGSG 372

  Fly   432 AKFVPLSLPPKPTEFVANRPFVFAV--RTPASVLFIGHVEYPT 472
            |:.:|:..|.:   ...|.||:..:  ....|::|:..:..|:
  Rat   373 AQTLPMETPRR---MKLNAPFLMMIYENLMPSMIFLARIYNPS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	87/362 (24%)
Serpina12	NP_620180.2	alpha-1-antitrypsin_like	51..408	CDD:239011	87/362 (24%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		7/17 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010