Protein Alignment nec and AGT

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001369746.2
• Gene: AGT / 183
• HGNCID: 333
• Length: 476
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 82/379 - (21%)
• Similarity: 152/379 - (40%)
• Gaps: 65/379 - (17%)

  Fly   128 VFSPFSVHALLALIY-GASDGKTFRELQKAGEFSKNAMAVAQ-DFESVIKYKKHLEG-------- 182
            |.||.:|...||.:| ||.|....|.....|...|:....:: |...|:...:.::|
Human   124 VLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRA 188

  Fly   183 ---ADLTLATKVYYNRELGGVNHSYDEYAKFYFSAG---------TEAVDMQNAKDTAAKINAWV 235
               |.|.|:|.|       ||..:...:.|..|..|         ..::|.......|.||:.::
Human   189 DSQAQLLLSTVV-------GVFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFM 246

  Fly   236 MDTTRNKIRDLVTPTDVDPQTQALLVNA-VYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMM-- 297
            ...|..|....:....||   ..|..|. |:|||:.: .|:.: ..|.:|...|.....|.|:
Human   247 QAVTGWKTGCSLMGASVD---STLAFNTYVHFQGKMK-GFSLL-AEPQEFWVDNSTSVSVPMLSG 306

  Fly   298 ------FND--DVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNR 354
                  ::|  |.:.:.::|          :.:|| .:|::.|:..:.|.| ::.|:..:..||.
Human   307 MGTFQHWSDIQDNFSVTQVP----------FTESA-CLLLIQPHYASDLDK-VEGLTFQQNSLNW 359

  Fly   355 VAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVRVSKILQKAYINV 419
            : .:|..:::.:.:|:...:...|:.:.|....:..:......:.||.:..:||.::|...:..:
Human   360 M-KKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFEL 423

  Fly   420 GEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAV--RTPASVLFIGHVEYP 471
                 ||......:.......|:..|...||||:|||  ::..::.|:|.|..|
Human   424 -----EADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	81/377 (21%)
AGT	NP_001369746.2	serpinA8_AGT	28..474	CDD:381010	82/379 (22%)