Protein Alignment nec and srp-6

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_504890.1
• Gene: srp-6 / 179125
• WormBaseID: WBGene00005647
• Length: 375
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 101/386 - (26%)
• Similarity: 173/386 - (44%)
• Gaps: 43/386 - (11%)

  Fly   108 DRFSSELFKEIIKSQS--------QQNV----VFSPFSVHALLALIYGASDGKTFRELQKAGEFS 160
            |..|.|....::.|::        |||:    ||||.|:...|:|::.|:.|:|..|::||....
 Worm     3 DSSSDEKMGLLLHSETDFGLSLLRQQNLTESFVFSPLSIALALSLVHVAAKGETRDEIRKALLNG 67

  Fly   161 KNAMAVAQDFESVIKYKKHLEGADLTLATKVYYNRELGGVNHSYDE----YAKFY-------FSA 214
            .....:.|.|.::        .|.|.:|.|   ..|:...||.:..    ..|.|       ::|
 Worm    68 ATDEELEQHFSNI--------SAGLLVAEK---GTEVNVANHIFSRKTFTIKKLYLNDVKKLYNA 121

  Fly   215 GTEAVDMQNAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDT 279
            |...::.::.:.:|..||.:|.:.|:..|:.::.|..:..:..|:|.||.||:..|:.:|....|
 Worm   122 GASQLNFEDQEASAEAINNFVSENTKGHIKKIINPDSISEELVAVLTNAFYFKANWQTKFKKEST 186

  Fly   280 SPYDFQHTNGRISKVAMMFNDDVYGLAELPELGA-TALELAYKDSATSMLILLPNETTGLGKMLQ 343
              |..:..:...||....|........:..|.|. ..|.|.|||::.::.|.||....||.:.||
 Worm   187 --YKREFFSSENSKRETEFLHSRNSNRKYSENGQFQVLSLPYKDTSFALSIFLPKTRFGLSEALQ 249

  Fly   344 QLSRPEFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVRV 408
            .|.  ...:.::........|.:.:||::.|....:...|..:|:.:.||.::.::...| .:.:
 Worm   250 NLD--SVTIQQLMSNTSNTLVNIAMPKWKIETALGLNRALMAVGIEKAFTDSADLSNFAD-GIYI 311

  Fly   409 SKILQKAYINVGEAGTEASAASYAKFVPLSL---PPKPTEFVANRPFVFAVRTPASVLFIG 466
            |:...||.|.|.|.||.|:||:...|...|:   ..:|.||.|:.||:|.:......||||
 Worm   312 SQAAHKALIEVDEDGTVAAAATTISFSLTSVFIPAEEPIEFTADHPFLFILSKDNHPLFIG 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	101/386 (26%)
srp-6	NP_504890.1	serpinL_nematode	16..374	CDD:381047	98/373 (26%)