Protein Alignment nec and SERPINA12

DIOPT Version :9

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001291390.1
• Gene: SERPINA12 / 145264
• HGNCID: 18359
• Length: 414
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 113/441 - (25%)
• Similarity: 199/441 - (45%)
• Gaps: 60/441 - (13%)

  Fly    59 PELGL----------RSLPGNPWTQNNQEAISDV-------VAVDLTKREPVTPPPNRPPPVFSY 106
            |.|||          :.|....::..|.:|:|:|       .|.:|.::.
Human     3 PTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQN--------------- 52

  Fly   107 MDRFSSELFKEIIKSQSQQNVVFSPFSVH-ALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDF 170
            || ...:|.|::......:|:..||.|:. |...|..||.| .|..|:::...|.|   ...:|.
Human    53 MD-LGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQD-STLDEIKQGFNFRK---MPEKDL 112

  Fly   171 ESVIKYKKH-----LEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAK 230
            .....|..|     .:...|::...::.::.| .....:.|.||.::||.|...:.||.:....:
Human   113 HEGFHYIIHELTQKTQDLKLSIGNTLFIDQRL-QPQRKFLEDAKNFYSAETILTNFQNLEMAQKQ 176

  Fly   231 INAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVA 295
            ||.::...|..||.:|:  .::||.|..||.|.::|:.||:|||....|...||........||.
Human   177 INDFISQKTHGKINNLI--ENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVP 239

  Fly   296 MMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFD-LNRVAHRL 359
            |||...:|.:....:|..|.||:.|:.:.|::.| ||:|    ||:.......:.| .:|....|
Human   240 MMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFI-LPDE----GKLKHLEKGLQVDTFSRWKTLL 299

  Fly   360 RRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLM-DQPVRVSKILQKAYINVGEAG 423
            .|:.|.|.:|:.......|:.:.|..:||.::|..:..:||:. .:.::|.:.:.||.:.:.|.|
Human   300 SRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERG 364

  Fly   424 TEASAASYAKFVPLSLPPKPTEFVANRPF---VFAVRTPASVLFIGHVEYP 471
            ||.:|.:.|:.:|:.   .|.....::|:   :::.:.| ||||:|.:..|
Human   365 TEGAAGTGAQTLPME---TPLVVKIDKPYLLLIYSEKIP-SVLFLGKIVNP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	SERPIN	108..468	CDD:238101	100/370 (27%)
SERPINA12	NP_001291390.1	serpinA12_vaspin	40..411	CDD:381026	103/402 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010