Protein Alignment nec and Serpinh1

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_033955.2
• Gene: Serpinh1 / 12406
• MGIID: 88283
• Length: 417
• Species: Mus musculus
• Alignment Length: 368
• Identity: 84/368 - (22%)
• Similarity: 159/368 - (43%)
• Gaps: 22/368 - (5%)

  Fly   114 LFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVIKYKK 178
            |::.:.|.|:.:|::.||..|.:.|.|:  :..||.....|.....|...:...:....:.:..:
Mouse    53 LYQAMAKDQAVENILLSPLVVASSLGLV--SLGGKATTASQAKAVLSAEKLRDEEVHTGLGELLR 115

  Fly   179 HLEGADLTLATKVYYNRELGGVNHSY-DEY---AKFYFSAGTEAVDMQNAKDTAAKINAWVMDTT 239
            .|..:.....|....:|..|..:.|: |::   :|.:::.....::.::.:.....||.|...||
Mouse   116 SLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWASQTT 180

  Fly   240 RNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVYG 304
            ..|:.::.  .||:....||||||::|:..|:.:|.........|..|......|.||....:|.
Mouse   181 DGKLPEVT--KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYN 243

  Fly   305 L--AELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVR 367
            .  .|..:|....:.||:|  .:|::||:|:....|.::.:.|::.:  |.....::::::||:.
Mouse   244 YYDDEKEKLQMVEMPLAHK--LSSLIILMPHHVEPLERLEKLLTKEQ--LKAWMGKMQKKAVAIS 304

  Fly   368 LPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD--QPVRVSKILQKAYINVGEAGTEASAAS 430
            |||...|...|:.:.|..||:.:....|......|.  :.:.::.:...........|.......
Mouse   305 LPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDI 369

  Fly   431 YAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYP 471
            |.:....|    |..|.|:.||:|.||  ...|:||||.:..|
Mouse   370 YGREELRS----PKLFYADHPFIFLVRDNQSGSLLFIGRLVRP 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	83/366 (23%)
Serpinh1	NP_033955.2	serpinH1_CBP1	35..416	CDD:381003	84/368 (23%)
		Prevents secretion from ER. /evidence=ECO:0000305	414..417