Protein Alignment nec and Agt

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_031454.4
• Gene: Agt / 11606
• MGIID: 87963
• Length: 477
• Species: Mus musculus
• Alignment Length: 478
• Identity: 90/478 - (18%)
• Similarity: 168/478 - (35%)
• Gaps: 113/478 - (23%)

  Fly    56 NPR----PELGLRSLPGNPWTQN-NQEAISDVVAVDLTKREPVTPPPNRPPPVFSYMDRFSSELF 115
            ||.    ||.....:|....|.. |::.:.|.:.:...|.|  .....|...|....:.....::
Mouse    47 NPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLE--DEDRKRAAQVAMIANFVGFRMY 109

  Fly   116 KEIIKSQS-QQNVVFSPFSVHALLALIYGASDGKTFRELQ-------KAGEFSKNAMAVAQDFES 172
            |.:.::.| ....:.||.::...|...|..|...|..:||       |.|:.:...     |...
Mouse   110 KMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRL-----DGHK 169

  Fly   173 VIKYKKHLEGADLTLA-----TKVYYNRELG-------GVNHSY-DEYAKFYFSAGTEAVDMQNA 224
            |:...:.::|..:|..     |.:..:..:|       .:.||: ...|.|..:....::|:...
Mouse   170 VLAALRAIQGLLVTQGGSSSQTPLLQSIVVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTD 234

  Fly   225 KDTAA-KINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNA-VYFQGRWE--------HEF----- 274
            ...|. |||.::...|..|:.   .|.:.......||.|. |:|||...        |||
Mouse   235 PVLATEKINRFIKAVTGWKMN---LPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNS 296

  Fly   275 ----ATMDTSPYDFQH---TNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLP 332
                ..|.:...:|||   |....|...:             .||..|          ::|::.|
Mouse   297 ISVSVPMISGTGNFQHWSDTQNNFSVTCV-------------PLGERA----------TLLLIQP 338

  Fly   333 NETTGLGKMLQQLSRPEFDLNRVAHRLRR------------QSVAVRLPKFQFEFEQDMTEPLKN 385
            :.|:              ||:||...:.|            :::.:.||:.:.....::.:.|..
Mouse   339 HCTS--------------DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAE 389

  Fly   386 LGVHQMFTPNSQVTKLMDQPVRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANR 450
            ..:..:....:.:..:.|...||.::|....:.: :||.|....:..: .|.|  |:..:...:.
Mouse   390 DKLPTLLGAEANLNNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQ-QPGS--PEALDVTLSS 450

  Fly   451 PFVFAV--RTPASVLFIGHVEYP 471
            ||:||:  :...::.|:|.|..|
Mouse   451 PFLFAIYEQDSGTLHFLGRVNNP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	77/422 (18%)
Agt	NP_031454.4	serpinA8_AGT	28..475	CDD:381010	90/478 (19%)