Protein Alignment lds and hisD

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_416524.1
• Gene: hisD / 946531
• ECOCYCID: EG10447
• Length: 434
• Species: Escherichia coli
• Alignment Length: 514
• Identity: 94/514 - (18%)
• Similarity: 172/514 - (33%)
• Gaps: 169/514 - (32%)

  Fly    15 DSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAESEKSDESDNSQ 79
            :::::.:|....::...|.:.:..:..|...:...::|..::..:|:....:|:.:|:..:....
E. coli     4 NTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALKV 68

  Fly    80 NSQE----SEDSEDDSVRPSA---------RNTKRKPLGIPSDSEDEEDELEQRALSP------- 124
            :::|    ||...|:..:..|         ...::.|   |.|.|.:.....|:...|
E. coli    69 SAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLP---PVDVETQPGVRCQQVTRPVASVGLY 130

  Fly   125 ---------------STRMSITGVR------PQDLSDDDSEIEYSDE---VQE----GPTEAPTA 161
                           :|..||.|.:      |..::|   ||.|:.:   ||:    |..:|..|
E. coli   131 IPGGSAPLFSTVLMLATPASIAGCKKVVLCSPPPIAD---EILYAAQLCGVQDVFNVGGAQAIAA 192

  Fly   162 EAV----VPRYTTQFA-GN--IQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDD 219
            .|.    ||:....|. ||  :...........|...:|..:|           |.|:|...|..
E. coli   193 LAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAG-----------PSEVLVIADSG 246

  Fly   220 ATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQ----PTIQAVLKQKTSPAAPRRSRIK 280
            ||        |.|                  ..|..|||    |..|.:|   .:|||....|:.
E. coli   247 AT--------PDF------------------VASDLLSQAEHGPDSQVIL---LTPAADMARRVA 282

  Fly   281 SEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAM----- 340
            ...::.::::...|..|       |..:|.:|.                    :.::||.
E. coli   283 EAVERQLAELPRAETAR-------QALNASRLI--------------------VTKDLAQCVEIS 320

  Fly   341 ----DEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWD-----ELSEAVNEIKPVY---- 392
                .|..|...|..:..|.::         ..|.|:...||.     :.:...|.:.|.|
E. coli   321 NQYGPEHLIIQTRNARELVDSI---------TSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTA 376

  Fly   393 -TGAQGMATFNNQKALTLESLKD-----LHVSLEDLPGPEVLA--EDPVGLKVSLMNHQ 443
             ..:.|:|.|  ||.:|::.|..     |..::|.|...|.|.  ::.|.|:|:.:..|
E. coli   377 TCSSLGLADF--QKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQ 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	34/183 (19%)
		DEXHc_TTF2	439..686	CDD:350830	1/5 (20%)
hisD	NP_416524.1	hisD	5..427	CDD:234853	92/505 (18%)