Protein Alignment lds and Smarca5

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_444354.2
• Gene: Smarca5 / 93762
• MGIID: 1935129
• Length: 1051
• Species: Mus musculus
• Alignment Length: 883
• Identity: 208/883 - (23%)
• Similarity: 338/883 - (38%)
• Gaps: 272/883 - (30%)

  Fly   230 PPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDE 294
            ||...|||.    |:|||. ..:|.|...|      :...:||||..:.....|
Mouse    12 PPESAPSKP----SAAGAG-GSSSGNKGGP------EGGAAPAAPCAAGSGPAD----------- 54

  Fly   295 EMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVR 359
                        ::.|::|:   |..|.|..:|.:...|...::..|........::|:.:.|..
Mouse    55 ------------TEMEEVFD---HGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHF 104

  Fly   360 VVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDL-HVSLEDLP 423
            :.......|.:|.              ::||      |.......:...|.|:.|. |...|...
Mouse   105 IQPAAQKTPTSPL--------------KMKP------GRPRVKKDEKQNLLSVGDYRHRRTEQEE 149

  Fly   424 GPEVLAEDPVGLKV--------------SLMNHQKHALAWM-SWRERKLPRGGILADDMGLGKTL 473
            ..|:|.|......|              .|.::|...|.|: |..|..:  .|||||:|||||||
Mouse   150 DEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGI--NGILADEMGLGKTL 212

  Fly   474 TMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQ 538
            ..||.:...|:.:.:.                                   |..:|:.|.|.|..
Mouse   213 QTISLLGYMKHYRNIP-----------------------------------GPHMVLVPKSTLHN 242

  Fly   539 WESEVESKVSRQKLTVCVHHGNNRETKGKYLRD------YDIVVTTYQIVAREHKSLSAVFGVKW 597
            |.||.:..|...: :||:.  .::|.:..::||      :|:.||:|:::.:| ||:...|  .|
Mouse   243 WMSEFKKWVPTLR-SVCLI--GDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKE-KSVFKKF--NW 301

  Fly   598 RRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKK 662
            |.:::||||.::|.||:.|..|.:.:...|..|||||:||...::::||.||....|:....:..
Mouse   302 RYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDS 366

  Fly   663 WID-NKSAGGQ---NRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTV 723
            |.| |...|.|   .||:::::..:|||.||.::     .|||.|:...|.:.|.|.:...|..:
Mouse   367 WFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVE-----KSLPPKKEVKIYVGLSKMQREWYTRI 426

  Fly   724 MTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDI 788
            :                                  :||.:         ....||...:::   :
Mouse   427 L----------------------------------MKDID---------ILNSAGKMDKMR---L 445

  Fly   789 LVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVAN 853
            |.:|::||:.|.||.|.|
Mouse   446 LNILMQLRKCCNHPYLFD----------------------------------------------- 463

  Fly   854 AGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWT 918
            ..:.|||...|                    :|..::...||:.......||....:.::.||.|
Mouse   464 GAEPGPPYTTD--------------------MHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMT 508

  Fly   919 SVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHL 983
            .|||||.|:..........|:|..|...|||.:|.:|:.|:.|.|.:||..|||:|:||..|:.:
Mouse   509 RVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVV 573

  Fly   984 LLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKV-- 1046
            :|.|..||||::.||.||.:|:||.|.|.:::|:..:|||:||....:.||.|...|:...::
Mouse   574 ILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVD 638

  Fly  1047 --------------------------SSKLTIDDLKGL 1058
                                      .|::|.:|:.|:
Mouse   639 QNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGI 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	186/779 (24%)
		DEXHc_TTF2	439..686	CDD:350830	75/257 (29%)
Smarca5	NP_444354.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		24/105 (23%)
		PLN03142	68..1011	CDD:215601	187/790 (24%)
		DEAH box	307..310		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1014..1051