Protein Alignment lds and Smarca1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001277637.1
• Gene: Smarca1 / 93761
• MGIID: 1935127
• Length: 1062
• Species: Mus musculus
• Alignment Length: 834
• Identity: 191/834 - (22%)
• Similarity: 336/834 - (40%)
• Gaps: 212/834 - (25%)

  Fly   243 SSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVS 307
            |.|.|:||........|   :..|::.:.||.......:|..:...::....:::..|:......
Mouse    15 SDARATVVVVEDEQPGP---STFKEEGAAAAATEGTTATEKGEKKEKITSPFQLKLAAKASKSEK 76

  Fly   308 DAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPA-VRVVKPTLNPPRAP 371
            :.:..:|:....:|.|..: .||.:.|.::..:...:|.....:....|. :::.:|.:......
Mouse    77 EMDPEYEEKMVNMPLKADR-AKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRVKKDDKQ 140

  Fly   372 SIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLK 436
            |:         .:|.:.:...|..:      ..:.|..||.|..:|.:.....|..:...|
Mouse   141 SL---------ISVGDYRHRRTEQE------EDEELLSESRKTSNVCVRFEVSPSYVKGGP---- 186

  Fly   437 VSLMNHQKHALAWM-SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDS 500
              |.::|...|.|: |..|..:  .|||||:|||||||..|:.:...|:.:.:.
Mouse   187 --LRDYQIRGLNWLISLYENGV--NGILADEMGLGKTLQTIALLGYLKHYRNIP----------- 236

  Fly   501 EDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETK 565
                                    |..:|:.|.|.|..|.:|.:..|...::...|   .:::.:
Mouse   237 ------------------------GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFV---GDKDVR 274

  Fly   566 GKYLRD------YDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRG 624
            ..::||      :|:.||:|::|.:| ||:...|  .||.:::||||.::|.||:.|..|.:.:.
Mouse   275 AAFIRDEMMPGEWDVCVTSYEMVIKE-KSVFKKF--HWRYLVIDEAHRIKNEKSKLSEIVREFKS 336

  Fly   625 KYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ----NRLNLLMKSLMLR 685
            ..|..|||||:||...:::|||.||....|:....:..|.|.|:..|.    .||:.::|..:||
Mouse   337 TNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLR 401

  Fly   686 RTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSD 750
            |.|..::     .|||.|:...|.:.|.|.:...|..::.               ::.|
Mouse   402 RIKTDVE-----KSLPPKKEIKIYLGLSKMQREWYTKILM---------------KDID------ 440

  Fly   751 ANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQ 815
                    :.:.:|...||.                 :|.:|::||:.|.||.|.|
Mouse   441 --------VLNSSGKMDKMR-----------------LLNILMQLRKCCNHPYLFD--------- 471

  Fly   816 TMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASK-----NL 875
                                                  ..:.|||...||..:..:.|     .|
Mouse   472 --------------------------------------GAEPGPPYTTDEHIVGNSGKMVALDKL 498

  Fly   876 LKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNG 940
            |.|                         :|....:.::.||.|.:||||.|:....|.....|:|
Mouse   499 LAR-------------------------IKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRLDG 538

  Fly   941 TIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRV 1005
            ..|.:.|::.::.||..|:.|.:.:||..|||:|:||..|:.::|.|..||||::.||.||.:|:
Mouse   539 QTPHEEREEAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRI 603

  Fly  1006 GQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKV----SSKLTIDDL 1055
            ||||.|.:::.:..:|||:||....:.||.|...|:...::    |:||..:::
Mouse   604 GQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEM 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	177/770 (23%)
		DEXHc_TTF2	439..686	CDD:350830	73/257 (28%)
Smarca1	NP_001277637.1	PLN03142	2..1061	CDD:215601	191/834 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..61		5/36 (14%)
		DEAH box	315..318		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	819..840