Protein Alignment lds and SNF2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_014933.3
• Gene: SNF2 / 854465
• SGDID: S000005816
• Length: 1703
• Species: Saccharomyces cerevisiae
• Alignment Length: 1142
• Identity: 260/1142 - (22%)
• Similarity: 450/1142 - (39%)
• Gaps: 330/1142 - (28%)

  Fly    11 DKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAESEKSDES 75
            |.::::..:.|..|.|  |...:|:..|.|:|:..| |..|.:|:|::||:::.       |:.:
Yeast   348 DSKDENFASVSPAGPS--SVHNAKNGTLDKNSQTVS-GTPITQTESKKEENETI-------SNVA 402

  Fly    76 DNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSITGVRPQDLSD 140
            ..:.||.::...:::..:|.    |..||.:..|...|                  |::..|:.|
Yeast   403 KTAPNSNKTHTEQNNPPKPQ----KPVPLNVLQDQYKE------------------GIKVVDIDD 445

  Fly   141 DD-------------SEIEYSDEVQEGPTEAPTAE-AVVPRYTTQFAGNIQNDLHSTIGAADSEV 191
            .|             |.|:|...:........|.| .|:|                 :|
Yeast   446 PDMMVDSFTMPNISHSNIDYQTLLANSDHAKFTIEPGVLP-----------------VG------ 487

  Fly   192 LDDSSGSDV---LILSNKETPI-----EILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGAS 248
            :|..:.:|:   ||..|.:|.:     ::|:  |:...:.:||..   ::..:..|.|...|...
Yeast   488 IDTHTATDIYQTLIALNLDTTVNDCLDKLLN--DECTESTRENAL---YDYYALQLLPLQKAVRG 547

  Fly   249 VVKTSKNLSQPTIQAVLKQKTSPAAPRRSR-IKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKL 312
            .|     |.....|..|...|.|....:.| |..:|..:.:|:..:.|:.||..|:.:.....|.
Yeast   548 HV-----LQFEWHQNSLLTNTHPNFLSKIRNINVQDALLTNQLYKNHELLKLERKKTEAVARLKS 607

  Fly   313 FEKVA----HKLPDKGSQIMK---RIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRA 370
            ..|.|    ::..||.::.:|   |:......|..|||    .|.::.....::.:|  .|...|
Yeast   608 MNKSAINQYNRRQDKKNKRLKFGHRLIATHTNLERDEQ----KRAEKKAKERLQALK--ANDEEA 666

  Fly   371 PSIDTLD-----------------WDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDL--- 415
             .|..||                 .|.|:.||.: :..||  :.|...:.::|  .|.:.||
Yeast   667 -YIKLLDQTKDTRITHLLRQTNAFLDSLTRAVKD-QQKYT--KEMIDSHIKEA--SEEVDDLSMV 725

  Fly   416 -----------------------HVSLEDL-PGPEVLAEDPVGLKVSLMNHQKHALAWM-SWRER 455
                                   |...||: ..|.:|    ||  .:|.::|...|.|| |....
Yeast   726 PKMKDEEYDDDDDNSNVDYYNVAHRIKEDIKKQPSIL----VG--GTLKDYQIKGLQWMVSLFNN 784

  Fly   456 KLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRK 520
            .|  .|||||:||||||:..||.:...   .||                    |::
Yeast   785 HL--NGILADEMGLGKTIQTISLLTYL---YEM--------------------KNI--------- 815

  Fly   521 DTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKGKYLR--DYDIVVTTYQIVA 583
               ||..||:.|.|.|..|.||........:........|.|:.|...:|  ::|:|:||::.:.
Yeast   816 ---RGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYII 877

  Fly   584 REHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAV-CDLRGKYRWALTGTPIQNKELDVYALLK 647
            :|...||.   |||..:|:||.|.::|.:|:.||.: ......||..|||||:||...:::|||.
Yeast   878 KERALLSK---VKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLN 939

  Fly   648 FLRCSPFDDLHTWKKWIDNKSA--GGQN--------------RLNLLMKSLMLRRTKAQLQSDGK 696
            |:....|:.:.::.:|.:...|  |||:              ||:.:::..:|||.|..::.:
Yeast   940 FVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKE-- 1002

  Fly   697 LNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKD 761
               ||:|..::::..:...:..:||.::.| |.||                           |.|
Yeast  1003 ---LPDKVEKVVKCKMSALQQIMYQQMLKY-RRLF---------------------------IGD 1036

  Fly   762 PNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDT 826
            .|      ::|...:.|...::         ::|::||.||.:.:.:.|
Yeast  1037 QN------NKKMVGLRGFNNQI---------MQLKKICNHPFVFEEVED---------------- 1070

  Fly   827 PEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSK 891
                   |:|....|:             ||                           :.|.:.|
Yeast  1071 -------QINPTRETN-------------DD---------------------------IWRVAGK 1088

  Fly   892 INMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFND 956
            ..::.:||..  ||::..:.::..|.|.::||:.|.|....:..|.|:|......|.:::..||.
Yeast  1089 FELLDRILPK--LKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNA 1151

  Fly   957 RNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDT 1021
            .:::....:||..|||:||||..|:.:::.|..|||..:.|||||.:|:|||..|.|.:.:..::
Yeast  1152 PDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNS 1216

  Fly  1022 VEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGL 1058
            ||:.|.....||||:...|:...|..:|.|.::.:.|
Yeast  1217 VEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEAL 1253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	196/824 (24%)
		DEXHc_TTF2	439..686	CDD:350830	77/266 (29%)
SNF2	NP_014933.3	QLQ	248..281	CDD:462622
		HSA	<617..656	CDD:462194	9/42 (21%)
		PLN03142	650..>1297	CDD:215601	184/771 (24%)
		SnAC	1303..1369	CDD:464219
		Bromo_SNF2	1550..1652	CDD:99950