Protein Alignment lds and RAD5

DIOPT Version :9

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_013132.1
• Gene: RAD5 / 850719
• SGDID: S000004022
• Length: 1169
• Species: Saccharomyces cerevisiae
• Alignment Length: 1297
• Identity: 306/1297 - (23%)
• Similarity: 498/1297 - (38%)
• Gaps: 427/1297 - (32%)

  Fly    57 EEEESQ--------SSETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDE 113
            |:||.:        :|||:.:.||:..::...:....|.:||.|           :.:...:|.|
Yeast     5 EQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDDDDVV-----------VSVSDTTEGE 58

  Fly   114 EDELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQN 178
            .|    |::.|..|                |||     :||..:..|.   :.|...:...::..
Yeast    59 GD----RSIVPVRR----------------EIE-----EEGQNQFITE---LLRIIPEMPKDLVM 95

  Fly   179 DLHSTIGAAD-------SEVLDDSSGSDVLILSNKETPIEILSSTD------------------- 217
            :|:...|:.:       |...|.:||:.:..:.:....:..||.|.
Yeast    96 ELNEKFGSQEEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGF 160

  Fly   218 ------DDATTNKE--------NMSGPPFERPSKSLS----PRSSAGASVVKTSKNLSQPTIQAV 264
                  :|..|.|.        .|:..|..||.|..|    .|||...|..|...:..
Yeast   161 RNQTRLEDKVTWKRFIGALQVTGMATRPTVRPLKYGSQMKLKRSSEEISATKVYDSRG------- 218

  Fly   265 LKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAE--------------------------KR 303
             ::|.|.|:..|          :..:.||.|:.:::|                          ||
Yeast   219 -RKKASMASLVR----------IFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDNKR 272

  Fly   304 VQVSDA----------EKLFEKVAHKLPDKGSQIMKRIDT---LRRE----------LAMDEQWI 345
            :.:.|:          ..:||:     .:.|..:|||..|   .:||          ...||:
Yeast   273 LSIGDSFILQLDCFLTSLIFEE-----RNDGESLMKRRRTEGGNKREKDNGNFGRTLTETDEE-- 330

  Fly   346 SALRVQQSNVPAVRV-----VKPTLNPPRA-----------PSIDTLDWDELSEAVNEIKPVYTG 394
              |..:...:..:::     :||.|:..:|           |.|..||.||:..  |::..|:..
Yeast   331 --LESRSKRLALLKLFDKLRLKPILDEQKALEKHKIELNSDPEIIDLDNDEICS--NQVTEVHNN 391

  Fly   395 AQGMATFNNQKALTLESLKDLH------VSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWM--- 450
            .:.  |.:.::.:.|..||..:      .||:.||..|...:   ..|:.|.|:||..|.||
Yeast   392 LRD--TQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRD---VFKLELRNYQKQGLTWMLRR 451

  Fly   451 -----------------------SWRERKLP---------------------------------- 458
                                   .|::.|.|
Yeast   452 EQEFAKAASDGEASETGANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYANLHSGEFSL 516

  Fly   459 ---------RGGILADDMGLGKTLTMISSVLACKNGQEMSEGK----DESSDSDS-----EDDKN 505
                     :||||:|:||||||:...|.||:|.:..::.:.|    :.::.||:     :|:|
Yeast   517 AKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENTAVSDNLPSTWQDNK- 580

  Fly   506 KKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRE------T 564
            |...|.|              ||:|.|.|||.||.:|.....:...:...|::|.|..      |
Yeast   581 KPYASKT--------------TLIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVSSLKTLLT 631

  Fly   565 KGKYLRDYDIVVTTYQIVARE---HKS----------LSAVFGVKWRRIILDEAHVVRNHKSQSS 616
            |.|  ....:|:|||.||..|   |..          .|.:|.|.:.|||:||.|.:||..:.:|
Yeast   632 KTK--TPPTVVLTTYGIVQNEWTKHSKGRMTDEDVNISSGLFSVNFYRIIIDEGHNIRNRTTVTS 694

  Fly   617 LAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQNR-----LN 676
            .||..|:||.:|.||||||.|:..|:|:|:|||...|:..::.||.::.........:     :|
Yeast   695 KAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKTFVSTPFESKNYKQAFDVVN 759

  Fly   677 LLMKSLMLRRTKAQLQSDGK-LNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAE 740
            .:::.::|||||.....||| |..||.||:.:..:...|            |:.|..:||..:||
Yeast   760 AILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSK------------SQDLLYKFLLDKAE 812

  Fly   741 RETDFNY-RSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGL 804
            ....... |.|..|                              |...|||.:|||||:||||||
Yeast   813 VSVKSGIARGDLLK------------------------------KYSTILVHILRLRQVCCHPGL 847

  Fly   805 IDAMLDGEESQTMGDHSSDSDTPEIDLL------------------AQLNKLAITDTSTDGQQSV 851
            |.:..:.:|..:..:......|.|:|.|                  |.:.:|.:........||:
Yeast   848 IGSQDENDEDLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSL 912

  Fly   852 ANAGDDGPPLLPDEARIAKA-----------------SKNL-LK--------------------- 877
            ..:.....|:..|:|...:.                 |||| ||
Yeast   913 ECSICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRNQIDACRLLALVQTNS 977

  Fly   878 -RSNPVFNLHRPSSKINMVIQILKTSIL---KSSDDKAIVVSQWTSVLDILRDHL----SKDGVA 934
             ..|..|..:.|:||.:.:..:||...|   .|:.::.::.||:::.||||...|    |||...
Yeast   978 NSKNLEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEKELTHTFSKDVAK 1042

  Fly   935 TLSLNGTIPVKNRQDIVNEF--NDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQ 997
            ....:|.:.:|.|..::.:|  .|.:.|| :|||||.||||||||..|:|..::|..|:|.:|.|
Yeast  1043 IYKFDGRLSLKERTSVLADFAVKDYSRQK-ILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQ 1106

  Fly   998 AQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGLF 1059
            |.||::|:||..:|.:.:|:..|::|:::..:|:||..:.:.:.|......|..|::::.||
Yeast  1107 AIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKRTIGEAMDTDEDERRKRRIEEIQMLF 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	SNF2_N	442..805	CDD:278600	127/466 (27%)
		DEXDc	459..634	CDD:238005	68/202 (34%)
		HELICc	885..1014	CDD:238034	51/137 (37%)
RAD5	NP_013132.1	HepA	116..1169	CDD:223627	278/1147 (24%)
		zf-C3HC4	914..960	CDD:306580	9/45 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I997
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000507
OrthoInspector	1	1.000	-	-		mtm9251
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2250
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940