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Protein Alignment lds and RAD54L

DIOPT Version :10

Sequence 1:	NP_524850.2	Gene:	lds / 45894	FlyBaseID:	FBgn0002542	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	NP_003570.2	Gene:	RAD54L / 8438	HGNCID:	9826	Length:	747	Species:	Homo sapiens

Alignment Length:	813	Identity:	200/813 - (24%)
Similarity:	314/813 - (38%)	Gaps:	233/813 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 SQIMKRIDTLRRELAMDEQW------------ISALRVQQSNVPAVRVVKP---TLNPPRAPSID 374
            ||:.||....|.  ..||.|            .|..::|:..:...|  ||   ..|.|  |.:|
Human     8 SQLAKRKPEGRS--CDDEDWQPGLVTPRKRKSSSETQIQECFLSPFR--KPLSQLTNQP--PCLD 66

  Fly   375 TLDWDE-----LSEAVNEIKPVYTGAQGMATFNNQKALTLESLKD-------------------- 414
            :...:.     ||:......|.|.|..|......::|....:|.|
Human    67 SSQHEAFIRSILSKPFKVPIPNYQGPLGSRALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQ 131

  Fly   415 LHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHAL--AWMSWRERKLP--RGGILADDMGLGKTL-- 473
            |.:..|.||...|:  ||:..|| |..||:..:  .|.....|::|  .|.|:||:|||||||
Human   132 LKLDKEKLPVHVVV--DPILSKV-LRPHQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQC 193

  Fly   474 -TMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLR 537
             |::.::|.            :|.:...|.||                      .:||.|:||::
Human   194 ITLMWTLLR------------QSPECKPEIDK----------------------AVVVSPSSLVK 224

  Fly   538 QWESEVESKVSRQKLTVCVHHGNNRETKGKYLRDY----------DIVVTTYQIVAREHKSLSAV 592
            .|.:||...:..:...:.:..|:..|...| |..:          .|::.:|: ..|.|
Human   225 NWYNEVGKWLGGRIQPLAIDGGSKDEIDQK-LEGFMNQRGARVSSPILIISYE-TFRLH------ 281

  Fly   593 FGVKWR----RIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSP 653
            .||..:    .:|.||.|.::|.::|:..|:..|....|..::||||||..|:.::|:.|:....
Human   282 VGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGI 346

  Fly   654 FDDLHTWKKWID-----NKSAG--------GQNRLNLL---MKSLMLRRTKAQLQSDGKLNSLPN 702
            ....|.:||..:     .:.|.        |:.||..|   :...::|||     ||.....||.
Human   347 LGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRT-----SDILSKYLPV 406

  Fly   703 KELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYY 767
            |..:::...|...:..:|:           :||.|.              ||....::
Human   407 KIEQVVCCRLTPLQTELYK-----------RFLRQA--------------KPAEELLE------- 439

  Fly   768 KMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLL 832
                       .|..|.|   |..:..|:::|.||.||......||...:|         .:||.
Human   440 -----------GKMSVSS---LSSITSLKKLCNHPALIYDKCVEEEDGFVG---------ALDLF 481

  Fly   833 AQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQ 897
                                      ||        ..:||.|    .|     :.|.|:.::..
Human   482 --------------------------PP--------GYSSKAL----EP-----QLSGKMLVLDY 503

  Fly   898 ILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKR 962
            ||..:..:|| ||.::||.:|..||:............:.|:||:.:|.|..:|..||..::...
Human   504 ILAVTRSRSS-DKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDF 567

  Fly   963 VLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIK 1027
            |.:||..|||.||||||||.|::.|..|||..:.||..|::|.||||...||:.:...|:|::|.
Human   568 VFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIF 632

  Fly  1028 GLQDKKLDLADGVLTGAK-VSSKLTIDDLKGLF 1059
            ..|..|..|:..|:...: |....::.:||.||
Human   633 QRQSHKKALSSCVVDEEQDVERHFSLGELKELF 665

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.