Protein Alignment lds and CHR4

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_199293.3
• Gene: CHR4 / 834510
• AraportID: AT5G44800
• Length: 2223
• Species: Arabidopsis thaliana
• Alignment Length: 1209
• Identity: 261/1209 - (21%)
• Similarity: 454/1209 - (37%)
• Gaps: 365/1209 - (30%)

  Fly     2 SSENSEYYSDKEEDSV-----------VNNSSLGRSRKSSRLSKSSR---------LSKSSRPSS 46
            |||..:..|.:|..|.           .:.:.||.:....|...||.         :..:..||.
plant   171 SSEKGKSISAEESKSTGKEVYSSPMDGCSTAELGHASADDRPDSSSHGEDDLGKPVIPTADLPSD 235

  Fly    47 AGVVI-----------------DETQSEEEESQSSETAESE-----KSDESDNSQNSQESEDSED 89
            ||:.:                 .|...|:.|..|||..|::     ::.:....:..:|..|.|.
plant   236 AGLTLLSCEDLSESKLSDTEKTHEAPVEKLEHASSEIVENKTVAEMETGKGKRKKRKRELNDGES 300

  Fly    90 -DSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQE 153
             :..:...:..|:....:.|.|:..:.....:......|:::     :.||...|:.|..::|::
plant   301 LERCKTDKKRAKKSLSKVGSSSQTTKSPESSKKKKKKNRVTL-----KSLSKPQSKTETPEKVKK 360

  Fly   154 GPTEAPTAEAVVPRYTTQF-------AGNIQNDLHSTIG--------AADSEVLDDSSGSDVLIL 203
            .|.|...|.....:.::..       .||:|  :|..:|        .:....|.|...||.|..
plant   361 LPKEERRAVRATNKSSSCLEDTNSLPVGNLQ--VHRVLGCRIQGLTKTSLCSALSDDLCSDNLQA 423

  Fly   204 SN------KETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKN-LSQPTI 261
            ::      ::|..|::.:.|...::::...|........|.:...:.....:|:..:. ||:...
plant   424 TDQRDSLVQDTNAELVVAEDRIDSSSETGKSSRDSRLRDKDMDDSALGTEGMVEVKEEMLSEDIS 488

  Fly   262 QAVLKQKTSPAAPRRSRIKSEDQKV------VSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKL 320
            .|.|.:          .:..||.||      |.:.:.:|..::..||.. |:| |::.|.||.|.
plant   489 NATLSR----------HVDDEDMKVSETHVSVERELLEEAHQETGEKST-VAD-EEIEEPVAAKT 541

  Fly   321 PDKGSQ------IMKRID----------------TLRREL-------------AMDEQW-----I 345
            .|...:      ::|.:|                ..:|:|             ..:::|     |
plant   542 SDLIGETVSYEFLVKWVDKSNIHNTWISEAELKGLAKRKLENYKAKYGTAVINICEDKWKQPQRI 606

  Fly   346 SALRV-QQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAV-------------NEIKPVYTGAQ 396
            .|||| ::.|..|  .||.|     ..:.|...|:.|.|.:             .|.|.:...::
plant   607 VALRVSKEGNQEA--YVKWT-----GLAYDECTWESLEEPILKHSSHLIDLFHQYEQKTLERNSK 664

  Fly   397 GMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLK-VSLMNHQKHALAWM--SWRERKLP 458
            |..|....:.:|                   |.|.|..|: .:|..||..||.|:  .|.:.|
plant   665 GNPTRERGEVVT-------------------LTEQPQELRGGALFAHQLEALNWLRRCWHKSK-- 708

  Fly   459 RGGILADDMGLGKTLT---MISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRK 520
             ..||||:||||||::   .:||:..     |....:.
plant   709 -NVILADEMGLGKTVSASAFLSSLYF-----EFGVARP--------------------------- 740

  Fly   521 DTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKGK-YLRDYD----------- 573
                  .||:.|.|.:..|.||.  .:....|.|..:||:   .||: .:|||:
plant   741 ------CLVLVPLSTMPNWLSEF--SLWAPLLNVVEYHGS---AKGRAIIRDYEWHAKNSTGTTK 794

  Fly   574 --------IVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWAL 630
                    :::|||::|..:...|.   ||.|..:::||.|.::|.:|:....:.....::|..|
plant   795 KPTSYKFNVLLTTYEMVLADSSHLR---GVPWEVLVVDEGHRLKNSESKLFSLLNTFSFQHRVLL 856

  Fly   631 TGTPIQNKELDVYALLKFLRCSPFDDLHTW-KKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSD 694
            ||||:||...::|.||.||:.|.|..|.:: :::.|..||.....|..|:...||||.|..
plant   857 TGTPLQNNIGEMYNLLNFLQPSSFPSLSSFEERFHDLTSAEKVEELKKLVAPHMLRRLKKD---- 917

  Fly   695 GKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQI 759
             .:.::|.|..|::.:.|...:...|:.::|.                   ||
plant   918 -AMQNIPPKTERMVPVELTSIQAEYYRAMLTK-------------------NY------------ 950

  Fly   760 KDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDS 824
                        :..|..|  |.|....:|.::::||::|.||.||    .|.|
plant   951 ------------QILRNIG--KGVAQQSMLNIVMQLRKVCNHPYLI----PGTE----------- 986

  Fly   825 DTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPS 889
              ||...|..|:.:.|                                              :.|
plant   987 --PESGSLEFLHDMRI----------------------------------------------KAS 1003

  Fly   890 SKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKD-GVATLS-LNGTIPVKNRQDIVN 952
            :|:.::..:||  :|.....:.::.||.|.:||||.|:|:.: |..|.. ::|::.|.:||..:.
plant  1004 AKLTLLHSMLK--VLHKEGHRVLIFSQMTKLLDILEDYLNIEFGPKTFERVDGSVAVADRQAAIA 1066

  Fly   953 EFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFM 1017
            .||...| :.|.|||..|.|:|:||..|:.:::.|..:||..:.||.:|.:|:||.|.:::|:.:
plant  1067 RFNQDKN-RFVFLLSTRACGLGINLATADTVIIYDSDFNPHADIQAMNRAHRIGQSKRLLVYRLV 1130

  Fly  1018 CVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLK 1056
            ...:||:||..|..||| :.|.:......|.|...|.|:
plant  1131 VRASVEERILQLAKKKL-MLDQLFVNKSGSQKEFEDILR 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	196/836 (23%)
		DEXHc_TTF2	439..686	CDD:350830	73/272 (27%)
CHR4	NP_199293.3	PHD2_CHD_II	78..119	CDD:277007
		CD1_tandem	507..585	CDD:349307	16/79 (20%)
		CD2_tandem	600..653	CDD:349306	15/59 (25%)
		PLN03142	675..>1197	CDD:215601	165/679 (24%)
		DUF1087	<1306..1341	CDD:461922
		SANT_TRF	1705..1749	CDD:212558