DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lds and AT5G05130

DIOPT Version :9

Sequence 1:	NP_524850.2	Gene:	lds / 45894	FlyBaseID:	FBgn0002542	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	NP_196132.3	Gene:	AT5G05130 / 830395	AraportID:	AT5G05130	Length:	881	Species:	Arabidopsis thaliana

Alignment Length:	973	Identity:	269/973 - (27%)
Similarity:	401/973 - (41%)	Gaps:	241/973 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 FERPSKSLSPRSSAGASVVK---TSKNLSQPTIQAVLKQKTSPAAPRRSRIKSED---------- 283
            |..|| ||..|||..|..::   :|...::...|       ||..|  |:.:|:|
plant     7 FRAPS-SLRHRSSPMAQFLRRFSSSPMANEDEFQ-------SPVEP--SQQQSQDCVSESYLIGF 61

  Fly   284 -----------------QKVVSQV-----VYDEE-MRKLAEKRVQVSDAEKLFEKVAHKLPDKGS 325
                             :::|..|     |||.. :|.|..:..||...|:....|...:.|..:
plant    62 VIANIVGLKYYSGRINGREMVGLVREPLNVYDNNAIRVLNTRSEQVGHIERTVAAVLAPMIDSHT 126

  Fly   326 QIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWD-ELSEAVNEIK 389
            .:::.|....|..:...:....:.| .:.:.|...||.|::......|...|.. .||||| .:|
plant   127 IVVEGIVPNTRSNSNRYRIPCQIHV-FAKLEASSTVKSTISRGGLVLISESDTSFGLSEAV-VVK 189

  Fly   390 PVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDP-VGLKVSLMNHQKHALAWMSWR 453
                  :.|...:.:....:..|.|.:|.   |.|..|.||.| ..:|..|..|||..|.|:..|
plant   190 ------EQMGNGDKRSVDKIFKLVDENVK---LMGKLVAAEPPREVIKSELFAHQKEGLGWLLHR 245

  Fly   454 ER--KLP--------------------------RGGILADDMGLGKTLTMISSVLACKNGQEMSE 490
            |:  :||                          |||:.|||||||||||::|.:...:.|...:.
plant   246 EKSGELPPFWEEKDGEFLNTLTNYRSDKRPDPLRGGVFADDMGLGKTLTLLSLIAFDRYGNASTS 310

  Fly   491 GKDE---SSDSDSEDDKNKKR------KSVTGWKSK-----GRKDTRRGGTLVVCPASLLRQWES 541
            ...|   ..:.|..:.|.|||      :|||..|.|     |...::: .||:|||.|::..|.:
plant   311 TPTEEPLDGEGDKIEKKGKKRGRGKSSESVTRKKLKTDDVVGMNVSQK-TTLIVCPPSVISAWIT 374

  Fly   542 EVESKVSRQKLTVCVHHGNNRETKGKYLRDYDIVVTTYQIVAREHK-SLSAVFGVKWRRIILDEA 605
            ::|.......|.|.::||..|......|..||||:|||..:|.|.. ..|.|..::|.|||||||
plant   375 QLEEHTVPGILKVYMYHGGERTDDVNELMKYDIVLTTYGTLAVEESWEDSPVKKMEWLRIILDEA 439

  Fly   606 HVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWID----- 665
            |.::|..:|.|..||.|:...|||:|||||||...|:|:|:.|||..||.....|:..|.
plant   440 HTIKNANAQQSRVVCKLKASRRWAVTGTPIQNGSFDLYSLMAFLRFEPFSIKSYWQSLIQRPLGQ 504

  Fly   666 -NKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRT 729
             ||.  |.:||.:||.::.|||||     :..|..||.|.:....:.|..||..:|.
plant   505 GNKK--GLSRLQVLMATISLRRTK-----EKSLIGLPPKTVETCYVELSPEERQLYD-------- 554

  Fly   730 LFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLR 794
                  |...|          |.....|.|.  ||:..:.:.               .:|.::||
plant   555 ------HMEGE----------AKGVVQNLIN--NGSLMRNYS---------------TVLSIILR 586

  Fly   795 LRQIC-----CHP----------------------GLIDAMLDGEESQTMGDHSSDSDTP----- 827
            |||:|     |.|                      .|:.|:.|||          |.|.|
plant   587 LRQLCDDMSLCPPELRSFTTSTSVEDVTDKPELLQKLVAALQDGE----------DFDCPICISP 641

  Fly   828 -----------------EIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARI----AKA 871
                             .:..|.:...|......:..|..:.||    ||..||.:..    ||:
plant   642 PTNIIITRCAHIFCRACILQTLQRSKPLCPLCRGSLTQSDLYNA----PPPPPDSSNTDGEDAKS 702

  Fly   872 SKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATL 936
            |..              |||::.::.:|..|..::.:.|::|.||:..:|.:|...|...|...|
plant   703 STK--------------SSKVSALLSLLMASRQENPNTKSVVFSQFRKMLLLLETPLKAAGFTIL 753

  Fly   937 SLNGTIPVKNRQDIVNEF-NDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQD 1000
            .|:|.:.||.|..::.|| |.......|||.||.|.|.|:||..|:.:.|.|..|||.:|.||.|
plant   754 RLDGAMTVKKRTQVIGEFGNPELTGPVVLLASLKASGTGINLTAASRVYLFDPWWNPAVEEQAMD 818

  Fly  1001 RIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVL--TGAKVSSKLTIDDLKGLFGM 1061
            ||:|:|||:.|.:.:.:..:::|:|:..||.||.:||:...  ...|...::.::|:..|..:
plant   819 RIHRIGQKQEVKMIRMIARNSIEERVLELQQKKKNLANEAFKRRQKKDEREVNVEDVVALMSL 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	SNF2_N	442..805	CDD:278600	133/438 (30%)
		DEXDc	459..634	CDD:238005	73/189 (39%)
		HELICc	885..1014	CDD:238034	49/129 (38%)
AT5G05130	NP_196132.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	180	1.000	Domainoid score	I1043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132523at2759
OrthoFinder	1	1.000	-	-		FOG0000507
OrthoInspector	1	1.000	-	-		mtm1031
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45626
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020