Protein Alignment lds and PIE1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_187887.3
• Gene: PIE1 / 820463
• AraportID: AT3G12810
• Length: 2055
• Species: Arabidopsis thaliana
• Alignment Length: 1304
• Identity: 278/1304 - (21%)
• Similarity: 479/1304 - (36%)
• Gaps: 433/1304 - (33%)

  Fly    23 LGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEE----EESQ--------------------- 62
            |.:..:|.|..|.::..|.:..:|.| ::|:...||    ||.|
plant    58 LSKDFESERKWKLAQAKKVALRASKG-MLDQASREERKLKEEEQRLRKVALNISKDMKKFWMKVE 121

  Fly    63 -----SSETAESEKSDESDN-------SQNSQESEDSEDDSVRP--SARNTKRKPLGIPSDSEDE 113
                 ..:...:||..::.:       .|..:.|....::.|.|  ..:||..||| :..:|:.:
plant   122 KLVLYKHQLVRNEKKKKAMDKQLEFLLGQTERYSTMLAENLVEPYKQGQNTPSKPL-LTIESKSD 185

  Fly   114 EDELEQRALSPSTRMSITGVRPQ-----------DLSDDDSEIEYSD------------EVQEGP 155
            |:..||.....::...:....|:           :..||:..||..:            |..:..
plant   186 EERAEQIPPEINSSAGLESGSPELDEDYDLKSEDETEDDEDTIEEDEKHFTKRERQEELEALQNE 250

  Fly   156 TEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPI-----EILSS 215
            .:.| .|.::.|||   :|.:         :.::..:.|.:..::..:|...:|:     :.|:|
plant   251 VDLP-VEELLRRYT---SGRV---------SRETSPVKDENEDNLTSVSRVTSPVKDENQDNLAS 302

  Fly   216 TDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIK 280
            ...|...:|.|::.          |..:....||.:::.:.....|.........|.....| :|
plant   303 VGQDHGEDKNNLAA----------SEETEGNPSVRRSNDSYGHLAISETHSHDLEPGMTTAS-VK 356

  Fly   281 S----------EDQKVVSQVV-----YDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKR 330
            |          ::|:.|..|:     .|:|.....|:.:..:|.|...|::|  |..|.|::...
plant   357 SRKEDHTYDFNDEQEDVDFVLANGEEKDDEATLAVEEELAKADNEDHVEEIA--LLQKESEMPIE 419

  Fly   331 IDTLR-------RELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWD--ELSEAVN 386
            :...|       ::::.||. .|:..|.:.:     :|....|..:|    .||.|  :|:|...
plant   420 VLLARYKEDFGGKDISEDES-ESSFAVSEDS-----IVDSDENRQQA----DLDDDNVDLTECKL 474

  Fly   387 EIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVG---------------LK 436
            :.:|.....:|  ||:.   :..::.||....:.|.......|: |.|               ||
plant   475 DPEPCSENVEG--TFHE---VAEDNDKDSSDKIADAAAAARSAQ-PTGFTYSTTKVRTKLPFLLK 533

  Fly   437 VSLMNHQKHALAWM-SWRERKLPRGGILADDMGLGKTLTMISSV--LACKNGQEMSEGKDESSDS 498
            .||..:|...|.|: :..|:||  .|||||:||||||:..|:.:  |||..|.
plant   534 HSLREYQHIGLDWLVTMYEKKL--NGILADEMGLGKTIMTIALLAHLACDKGI------------ 584

  Fly   499 DSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRE 563
                           |          |..|:|.|.|::..||:|........|  :..:.|:.:|
plant   585 ---------------W----------GPHLIVVPTSVMLNWETEFLKWCPAFK--ILTYFGSAKE 622

  Fly   564 TKGK-----YLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLR 623
            .|.|     .|..:.:.:|||::|.::.|....   .||:.:||||||:::|.|||....:.:..
plant   623 RKLKRQGWMKLNSFHVCITTYRLVIQDSKMFKR---KKWKYLILDEAHLIKNWKSQRWQTLLNFN 684

  Fly   624 GKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAG---GQ--------NRLNL 677
            .|.|..|||||:||..:::::|:.||....|.....:|.|..|..||   ||        :||:.
plant   685 SKRRILLTGTPLQNDLMELWSLMHFLMPHVFQSHQEFKDWFCNPIAGMVEGQEKINKEVIDRLHN 749

  Fly   678 LMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERE 742
            :::..:|||.|..::     ..||:|...:|...|.|.:.|:|:..:              |..|
plant   750 VLRPFLLRRLKRDVE-----KQLPSKHEHVIFCRLSKRQRNLYEDFI--------------ASTE 795

  Fly   743 TDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLID- 806
            |.....|              |:::.|                   :.::::||::|.||.|.:
plant   796 TQATLTS--------------GSFFGM-------------------ISIIMQLRKVCNHPDLFEG 827

  Fly   807 ---------AMLDGEESQTMGDHSSDSDTPEIDLLA---QLNKLAITDTSTDGQQSVA------- 852
                     |.:|.:.|.|:.....:|...::||.|   ....|..:.||.:|.:..|
plant   828 RPIVSSFDMAGIDVQLSSTICSLLLESPFSKVDLEALGFLFTHLDFSMTSWEGDEIKAISTPSEL 892

  Fly   853 -----NAGDD--GPPLLPD-------------------EARIAKAS------------------- 872
                 |..||  ..||.|.                   |.||.::.
plant   893 IKQRVNLKDDLEAIPLSPKNRKNLQGTNIFEEIRKAVFEERIQESKDRAAAIAWWNSLRCQRKPT 957

  Fly   873 -----KNLL-------------------------------------------------------- 876
                 :.||
plant   958 YSTSLRTLLTIKGPLDDLKANCSSYMYSSILADIVLSPIERFQKMIELVEAFTFAIPAARVPSPT 1022

  Fly   877 ----KRSNPVFNLHRPSSKINMVIQILKTSI---------------------------------L 904
                |..:|||.......|:..::..|.:.|                                 |
plant  1023 CWCSKSDSPVFLSPSYKEKVTDLLSPLLSPIRPAIVRRQVYFPDRRLIQFDCGKLQELAMLLRKL 1087

  Fly   905 KSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVL-LLSL 968
            |....:|::.:|.|.:||:|...::..|...:.|:|:.|.:.||.::..||  .|.|..| :||.
plant  1088 KFGGHRALIFTQMTKMLDVLEAFINLYGYTYMRLDGSTPPEERQTLMQRFN--TNPKIFLFILST 1150

  Fly   969 TAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRI--KGLQD 1031
            .:||||:||:||:.::..|..|||.::.|||||.:|:||.:.|.||:.:...|:|:.|  |..|.
plant  1151 RSGGVGINLVGADTVIFYDSDWNPAMDQQAQDRCHRIGQTREVHIYRLISESTIEENILKKANQK 1215

  Fly  1032 KKLD 1035
            :.||
plant  1216 RVLD 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	221/963 (23%)
		DEXHc_TTF2	439..686	CDD:350830	78/265 (29%)
PIE1	NP_187887.3	HSA	36..106	CDD:214727	13/48 (27%)
		DEXQc_SRCAP	536..758	CDD:350761	78/265 (29%)
		DISARM_DrmD_b	554..1488	CDD:468472	178/764 (23%)
		SF2_C_SNF	1064..1199	CDD:350180	44/136 (32%)