Protein Alignment lds and BRM

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_973695.1
• Gene: BRM / 819210
• AraportID: AT2G46020
• Length: 2193
• Species: Arabidopsis thaliana
• Alignment Length: 1193
• Identity: 254/1193 - (21%)
• Similarity: 426/1193 - (35%)
• Gaps: 372/1193 - (31%)

  Fly     2 SSENSEYYSDKEEDSVVNNS---SLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQS 63
            :|.|...:| ||||:|.:..   :.|.|:....|.|                       |..|..
plant   543 ASSNGPIFS-KEEDNVGDTEVALTTGHSQLFQNLGK-----------------------EATSTD 583

  Fly    64 SETAESEKSD----ESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSP 124
            ..|.|.:::|    :||...:|...::...||       |..|...:.||.       .|..:.|
plant   584 VATKEEQQTDVFPVKSDQGADSSTQKNPRSDS-------TADKGKAVASDG-------SQSKVPP 634

  Fly   125 STRMSITGVRPQDLSDDDSEIEYSDEVQEGPT-EAPTAEAVVPRYTTQFAGNIQNDLHSTIGAAD 188
            ...      .||...|..|..:|     .||. :.|.....:..|.:..| |..|:|  |: |.|
plant   635 QAN------SPQPPKDTASARKY-----YGPLFDFPFFTRKLDSYGSATA-NANNNL--TL-AYD 684

  Fly   189 SEVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTS 253
            .:.|....|::  .||.|.|          |:......:.....||  |.:.|.......:.:..
plant   685 IKDLICEEGAE--FLSKKRT----------DSLKKINGLLAKNLER--KRIRPDLVLRLQIEEKK 735

  Fly   254 KNLSQPTIQAVLKQK---------TSPAAP--------RRSRIKSEDQKVVSQVVYDEEM----- 296
            ..||.  :|:.::::         :.|..|        .|.|::...|.:.:|....|:.
plant   736 LRLSD--LQSRVREEVDRQQQEIMSMPDRPYRKFVRLCERQRLEMNRQVLANQKAVREKQLKTIF 798

  Fly   297 ---RKLAEKRVQVSDAE--------KLFEKVAH---KLPDKGSQIMKRIDTLRRELAMDEQWISA 347
               :||.|....:.||.        |..||:..   |..|.|..  ||::.|:....  |::...
plant   799 QWRKKLLEAHWAIRDARTARNRGVAKYHEKMLREFSKRKDDGRN--KRMEALKNNDV--ERYREM 859

  Fly   348 LRVQQSNVPA------------VRVVKPTLNPPRAPSIDTLDWDELSEAVN-------------- 386
            |..||:|:|.            :...:..|:........|.:..|:.||.|
plant   860 LLEQQTNMPGDAAERYAVLSSFLTQTEDYLHKLGGKITATKNQQEVEEAANAAAVAARLQGLSEE 924

  Fly   387 EIKPVYTGAQGMATFNNQ----KALTLESLKDLHVSLEDLPGPEVLAEDPVGLKV-SLMNHQKHA 446
            |::...|.|:......|:    .|....|..:.:.:|..... ||:...|..|:. :|.::|...
plant   925 EVRAAATCAREEVVIRNRFTEMNAPKENSSVNKYYTLAHAVN-EVVVRQPSMLQAGTLRDYQLVG 988

  Fly   447 LAWM-SWRERKLPRGGILADDMGLGKT---LTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKK 507
            |.|| |....||  .|||||:||||||   :.:|:.::..|...
plant   989 LQWMLSLYNNKL--NGILADEMGLGKTVQVMALIAYLMEFKGNY--------------------- 1030

  Fly   508 RKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVES---KVSRQKLTVCVHHGNNRETKGKYL 569
                             |..|::.|.::|..|:||:.:   .||      |:::...::.:.|..
plant  1031 -----------------GPHLIIVPNAVLVNWKSELHTWLPSVS------CIYYVGTKDQRSKLF 1072

  Fly   570 RD------YDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRW 628
            ..      ::::||||:.:..:...||.   |.|:.||:|||..:::.:|..:..:...|.:.|.
plant  1073 SQEVCAMKFNVLVTTYEFIMYDRSKLSK---VDWKYIIIDEAQRMKDRESVLARDLDRYRCQRRL 1134

  Fly   629 ALTGTPIQNKELDVYALLKFLRCSPFDD---LHTW---------------KKWID-NKSAGGQNR 674
            .|||||:||...::::||..|....||:   .|.|               ..|:: .|.....:|
plant  1135 LLTGTPLQNDLKELWSLLNLLLPDVFDNRKAFHDWFAQPFQKEGPAHNIEDDWLETEKKVIVIHR 1199

  Fly   675 LNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRA 739
            |:.:::..||||....::     .|||.|...::...:...:..||..:.. :.||       |.
plant  1200 LHQILEPFMLRRRVEDVE-----GSLPAKVSVVLRCRMSAIQSAVYDWIKA-TGTL-------RV 1251

  Fly   740 ERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGL 804
            :.: |...|:..| |.|             ..|..|...::           .:.||:.|.||.|
plant  1252 DPD-DEKLRAQKN-PIY-------------QAKIYRTLNNR-----------CMELRKACNHPLL 1290

  Fly   805 IDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIA 869
                    ......|.|.|.      |:....||.|.|                        ||
plant  1291 --------NYPYFNDFSKDF------LVRSCGKLWILD------------------------RI- 1316

  Fly   870 KASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVA 934
                 |:|                          |:.:..:.::.|..|.:||||.::|....:.
plant  1317 -----LIK--------------------------LQRTGHRVLLFSTMTKLLDILEEYLQWRRLV 1350

  Fly   935 TLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQ 999
            ...::||..:::|:..:.:|||.:....:.|||:.|.|.||||..|:.:::.|...||:.|.||.
plant  1351 YRRIDGTTSLEDRESAIVDFNDPDTDCFIFLLSIRAAGRGLNLQTADTVVIYDPDPNPKNEEQAV 1415

  Fly  1000 DRIYRVGQKKNV-IIYKFMCVDTVEQR---------------------------IKGL-----QD 1031
            .|.:|:||.:.| :||....|:.:...                           |:||     |.
plant  1416 ARAHRIGQTREVKVIYMEAVVEKLSSHQKEDELRSGGSVDLEDDMAGKDRYIGSIEGLIRNNIQQ 1480

  Fly  1032 KKLDLADGVLTGAKVSSKLTIDD 1054
            .|:|:||.|:...:...:.|.::
plant  1481 YKIDMADEVINAGRFDQRTTHEE 1503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	189/868 (22%)
		DEXHc_TTF2	439..686	CDD:350830	68/278 (24%)
BRM	NP_973695.1	QLQ	462..497	CDD:214931
		PLN03142	831..>1438	CDD:215601	171/769 (22%)
		DEXHc_SMARCA2_SMARCA4	978..1213	CDD:350754	70/283 (25%)
		BROMO	1900..2004	CDD:197636