Protein Alignment lds and chd9

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_031756017.1
• Gene: chd9 / 733830
• XenbaseID: XB-GENE-1217623
• Length: 2891
• Species: Xenopus tropicalis
• Alignment Length: 1119
• Identity: 241/1119 - (21%)
• Similarity: 406/1119 - (36%)
• Gaps: 375/1119 - (33%)

  Fly    21 SSLGRSRKSSRLSKSSRLSKSSRPSSAG---------------VVIDETQSEEEESQSSETAESE 70
            ||.|:..|..|..||....|..:.:.||               :.:...|..:.|| |.:.::|:
 Frog   543 SSEGKDEKRGRKGKSKPKEKEGKKTKAGLSSELKEKKKIGKLIITLGRKQKRKMES-SDDVSDSD 606

  Fly    71 KSDESDNSQNSQE--------SEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTR 127
            ::....|.::.||        .:|......|.|.|..|||.  ...|.|.::.|.|.:|
 Frog   607 RAPRVHNDEDLQEFAWRTDHLHQDQTGSMKRRSNRQVKRKK--YVEDVEGKQSEDEPKA------ 663

  Fly   128 MSITGVRPQDLSDDDSEIEYSDEVQ---EGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADS 189
                .|:|:   .:.:.:.....:|   |.|:|                             .|:
 Frog   664 ----NVKPK---KNSTSLPVEQPLQLFVENPSE-----------------------------EDA 692

  Fly   190 EVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSK 254
            .::|                 :||:|    ....||..||...|           .....|| .|
 Frog   693 AIVD-----------------KILAS----RIAKKETSSGTFVE-----------VEEYYVK-YK 724

  Fly   255 NLSQ-----PTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFE 314
            |.|.     .|.|.:||.|         ||   .||:               ||.::..|::
 Frog   725 NYSYLHCEWATEQQLLKDK---------RI---HQKI---------------KRFKIRQAQR--- 759

  Fly   315 KVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWD 379
              ||...|...::... |.:..:..::   :|..:.:.:..|.:..:....:.|...|    .|
 Frog   760 --AHFFADMEEELFNS-DYIEVDRVLE---VSLCQDKDTGEPVIYYLVKWCSLPYEDS----TW- 813

  Fly   380 ELSEAVNEIKPVYTGAQGMATFNNQKALTLE----------SLKDLHVSLEDLPGPEVLAEDPVG 434
            ||.|.|::.|        :..|...:||..:          |.|.::.|.|...|.:
 Frog   814 ELKEDVDQAK--------IDEFEQLQALKPDARRVERPPPNSWKKINQSREYKIGNQ-------- 862

  Fly   435 LKVSLMNHQKHALAWM--SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSD 497
                |..:|...|.|:  :|..|   |..||||:||||||:..|:.:      ||:...:..
 Frog   863 ----LREYQLEGLNWLLFNWYNR---RNCILADEMGLGKTIQSITFL------QEIYLNRIP--- 911

  Fly   498 SDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNN- 561
                                       |..|::.|.|.:..||.|..:...   |.|.|:||:.
 Frog   912 ---------------------------GPFLIIAPLSTIANWEREFRTWTD---LNVVVYHGSMI 946

  Fly   562 ------------RETKGKYL---RDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNH 611
                        |:::|:.:   ..:..::||::::......|:|   ::||.:|.||||.::|.
 Frog   947 SRQMIQQYEMYFRDSQGRIIWGSYKFHAIITTFEMILGGCPELNA---IEWRCVIFDEAHRLKNK 1008

  Fly   612 --KSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTW-KKWIDNKSAGGQN 673
              |....|.:.:|  :::..|||||:||...::::||.||....|....|: :::.|.|:.....
 Frog  1009 NCKLLEGLKLMNL--EHKVLLTGTPLQNTVEELFSLLHFLEPQRFPSESTFMQEFGDLKTEEQVQ 1071

  Fly   674 RLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQR 738
            :|..::|.:||||.|..::     ..|..||..:||:.|...:...|:.::..:   || ||.:.
 Frog  1072 KLQAILKPMMLRRLKEDVE-----KKLAPKEETIIEVELTNIQKKYYRAILEKN---FA-FLSKG 1127

  Fly   739 AERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPG 803
            |         ..||.|                                :::..::.||:.|.||.
 Frog  1128 A---------GQANVP--------------------------------NLVNTMMELRKCCNHPY 1151

  Fly   804 LIDAMLDGEESQTMGDHSSDSDTPEID-----LLAQLNKLAITDTSTDGQQSVANAGDDGPPLLP 863
            ||    .|.|.:.:|:.....:....|     ::....||.:.|                 .|||
 Frog  1152 LI----KGAEEKILGEFRETYNQMAADFYLQAMIQSAGKLVLID-----------------KLLP 1195

  Fly   864 DEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHL 928
            .                                       :|:...|.::.||....||||.|:|
 Frog  1196 K---------------------------------------MKAGGHKVLIFSQMVRCLDILEDYL 1221

  Fly   929 SKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQ 993
            .........::|.:....||..::.|:..::.:.|.||...|||:|:||..|:..::.|..||||
 Frog  1222 MHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQ 1286

  Fly   994 LEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLT----------GAKVSS 1048
            .:.|||.|.:|:||.|.|.:|:.:..::.|:.:......||.|...||.          |.:..|
 Frog  1287 NDLQAQARCHRIGQNKAVKVYRLITRNSYEREMFDRASLKLGLDKAVLQSMSGRENSVGGIQQLS 1351

  Fly  1049 KLTIDDL--KGLFG 1060
            |..|:||  :|.:|
 Frog  1352 KKEIEDLLRRGAYG 1365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	171/789 (22%)
		DEXHc_TTF2	439..686	CDD:350830	68/267 (25%)
chd9	XP_031756017.1	CDC27	<469..675	CDD:462819	32/147 (22%)
		CD1_tandem_CHD5-9_like	689..753	CDD:349315	27/152 (18%)
		CD2_tandem_CHD5-9_like	774..831	CDD:349310	12/72 (17%)
		PLN03142	859..>1488	CDD:215601	157/676 (23%)
		BRK	2477..2518	CDD:462196
		BRK	2552..2596	CDD:197800