Protein Alignment lds and rad54l2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001076824.1
• Gene: rad54l2 / 733747
• XenbaseID: XB-GENE-5829376
• Length: 1396
• Species: Xenopus tropicalis
• Alignment Length: 1139
• Identity: 235/1139 - (20%)
• Similarity: 398/1139 - (34%)
• Gaps: 402/1139 - (35%)

  Fly    52 DETQSEEEESQSSETAESEKSDESDN--------------SQNSQESEDSEDDSVRPSARNT--- 99
            ::.:.|||:.:..:..|.|:.||.||              |||:...|||.:.......|:|
 Frog    16 EDMEEEEEDDEDDDEEEEEEEDEEDNDGDDEDDKQDINEKSQNAALGEDSPEQGEEGWKRSTTSG 80

  Fly   100 ---------KRKPLGIPSDSED------EEDELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSD 149
                     |:|.|..|::...      .||:||          |:|....|:      |:|...
 Frog    81 QSGQESDEAKKKRLQKPANLRRNIRKLLREDQLE----------SVTKTAQQE------ELERRK 129

  Fly   150 EVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAAD-------SEV--LDDSSG-SD----V 200
            .:::...:.| ....:|..:..|   :|.::.  :.|||       .|:  ||.||| ||    |
 Frog   130 RLEQQRKDYP-LPLTLPPVSLDF---LQEEIE--LRAADVSQLVKSQEIICLDSSSGESDDEGKV 188

  Fly   201 LILSNKETPIEILSSTDD----------------DATTNKENMSGPPFERPSKSLSPRSSAGASV 249
            ...|.|:..||:.|..:|                |.||  || ||   ...:.:|:.....|..:
 Frog   189 KSHSIKDEIIELSSGEEDNLQISDNADSTNEVDGDITT--EN-SG---SHVNDALNQADHLGRVL 247

  Fly   250 VKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFE 314
            |    |::.|.     .:|....||:.:|.....|....:.:||    .|.|...:.|.:.....
 Frog   248 V----NINHPP-----NEKDIFLAPQLARAVKSHQIGGIRFLYD----NLVESLERFSGSSGFGC 299

  Fly   315 KVAHKLP-DKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTL-D 377
            .:||.:. .|..|::..:|.|               .|.::...|..:.|         ::|| :
 Frog   300 ILAHSMGLGKTLQVISFLDVL---------------FQHTSAKTVLAIVP---------VNTLQN 340

  Fly   378 WDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAED-------PVGL 435
            |                   :|.||..                 ||.||.|.:|       |...
 Frog   341 W-------------------LAEFNMW-----------------LPPPESLPKDHNQELVQPRAF 369

  Fly   436 KVSLMNHQKHALA--------WMSWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGK 492
            ||..||.:....|        |.:       .||:|.....:.:.|::..|..|.:..:......
 Frog   370 KVHTMNDEHKTTAARAKVVNDWAT-------DGGVLLMGYEMYRLLSLKKSFTAGRKKKSKKAAG 427

  Fly   493 DESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVH 557
            ....|.|.||.:.:..|.:.      :..:|.|..:|:|
 Frog   428 PVIIDLDEEDRQQEMLKGIE------KALSRPGPDVVIC-------------------------- 460

  Fly   558 HGNNRETKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDL 622
                                                         ||.|.::|..:.:|.|:.::
 Frog   461 ---------------------------------------------DEGHRIKNCHASTSQALKNI 480

  Fly   623 RGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ--------------- 672
            |.:.|..|||.|:||..::.:.::.|:|.........:....:.....||
 Frog   481 RSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCVDSTPQDKRLMRYR 545

  Fly   673 -NRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLH 736
             :.|:.|::..:.||....|::     .||.||..:|.:.|.|           ..|.|:.:|:
 Frog   546 SHVLHSLLEGFVQRRGHTVLKA-----QLPFKEEHVILVRLSK-----------IQRDLYTEFM- 593

  Fly   737 QRAERETDFNYRSDANKPTYNQIKDP-NGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICC 800
                                |:.:|. |..:..::.                     |:...:||
 Frog   594 --------------------NRFRDAGNSGWLGLNP---------------------LKAFCVCC 617

  Fly   801 ----HPGLIDAMLDGEESQTMGDHSSDSDTPEID----LLAQLNKLAITDTSTDGQQSVANAGD- 856
                ||   |.:.:..:.:.:. :..|.|..::.    ..||..|:.:...|..     |..|:
 Frog   618 KIWNHP---DVLYEALQKENLA-NEQDLDVEDLGTNNRCNAQSGKIKVEPNSLG-----ALMGET 673

  Fly   857 ------DGPPLLPDEARIAKA-----SKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDK 910
                  .|..|.|...:..:.     :|.:|  |:.:....:.|.|:.::..:::.|:  ...||
 Frog   674 AHTKQLQGIVLNPSHEKANQVVTYEWAKEIL--SDYIPGQLQNSPKMVLLFHLIEESM--RMGDK 734

  Fly   911 AIVVSQWTSVLDILRDHLSK---------DG---------VATLSLNGTIPVKNRQDIVNEFNDR 957
            .:|.||..|.|.|:.:.|:|         ||         |....|:|:.....|:.::|:|||.
 Frog   735 ILVFSQSLSTLSIMEEFLAKRKMPIPAGSDGQEGHTWIRNVNYYRLDGSTSASERERLINQFNDP 799

  Fly   958 NNQK-RVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDT 1021
            :|:| .:.|||..||.:|:||||||.:::.|..|||..:|||..|:||.||:|...||:.:...|
 Frog   800 SNEKVWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQRKPCYIYRLVSDFT 864

  Fly  1022 VEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDL 1055
            :|::|...|..|..::|.|           :|||
 Frog   865 LEKKIYDRQITKQGMSDRV-----------VDDL 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	162/826 (20%)
		DEXHc_TTF2	439..686	CDD:350830	39/270 (14%)
rad54l2	NP_001076824.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		21/86 (24%)
		DEXHc_ARIP4	269..545	CDD:350827	67/423 (16%)
		HepA	<272..885	CDD:440319	164/842 (19%)
		DEAH box	461..464		2/2 (100%)
		LXXLL motif 1	549..553		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1117..1168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1194..1250
		LXXLL motif 2	1273..1277
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1396