Protein Alignment lds and chd9

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_005169069.3
• Gene: chd9 / 572355
• ZFINID: ZDB-GENE-030131-497
• Length: 2952
• Species: Danio rerio
• Alignment Length: 1132
• Identity: 243/1132 - (21%)
• Similarity: 411/1132 - (36%)
• Gaps: 397/1132 - (35%)

  Fly     3 SENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAG----VVIDETQSEEEESQS 63
            |.:|::.|.|...|        :|:...:.||.:|:.|||:|....    :||...:.:.:::.|
Zfish   615 SSSSQHRSHKAGSS--------KSKSKDKSSKKARIVKSSKPKQKAQIGKIVIKFGKKKRKKTDS 671

  Fly    64 SETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRM 128
            ||    |.||:...::.|.:    :|||.|.|.|..|||..
Zfish   672 SE----ELSDDDRPTRRSSK----DDDSKRRSNRKVKRKKY------------------------ 704

  Fly   129 SITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLD 193
                       :||.|...|||                                     :.:|:.
Zfish   705 -----------EDDGEARISDE-------------------------------------EMKVIV 721

  Fly   194 DSSGSDVLILSNKETPIEIL--SSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASV------V 250
            .:..|.    |||:..:::.  :.|::||....:.|:       |:.:....|.|..|      |
Zfish   722 KAKKSS----SNKKPAVQLFVENPTEEDAAVVDKIMA-------SRVVKKEVSPGVLVEIEEYFV 775

  Fly   251 KTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEK 315
            | .||.|....:...:|:.            |..|.:.|.:          ||.::..|:|
Zfish   776 K-YKNYSYLHCEWATEQQL------------EKDKRIQQKI----------KRFKIKQAQK---- 813

  Fly   316 VAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRV--------QQSNVPAVRVVKPTLNPPRAPS 372
             ||...|            ..|...:..::...||        :.|..|.|..:....:.|...|
Zfish   814 -AHFFAD------------IEEDPFNPDYVEVDRVLEVSYCEDKDSGEPVVYYLVKWCSLPYEDS 865

  Fly   373 IDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVG--- 434
                .| ||.|.|::.|                   :|..|.|..:   .|....:...|..
Zfish   866 ----TW-ELMEDVDQTK-------------------IEEFKKLQAA---KPHTNRMERPPASHWK 903

  Fly   435 ---------LKVSLMNHQKHALAWM--SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEM 488
                     .:.||.::|...:.|:  :|..|   |..||||:||||||:..|:.:      :|:
Zfish   904 KLEKSRKYCNENSLRDYQLEGVNWLLFNWYNR---RNCILADEMGLGKTIQSITFL------EEI 959

  Fly   489 SEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLT 553
            ..                     ||.|         |..|::.|.|.:..||.|..:..   .|.
Zfish   960 YR---------------------TGIK---------GPFLIIAPLSTIANWEREFRTWT---HLN 991

  Fly   554 VCVHHGN-------------NRETKGKYLRD---YDIVVTTYQIVAREHKSLSAVFGVKWRRIIL 602
            |.|:||:             .|:::|:.:|.   :..|:||::::......|:|   :.||.:|:
Zfish   992 VIVYHGSVVSRQMLQQYEMYCRDSQGRVIRGAYRFQAVITTFEMILGGCPELNA---IDWRCVII 1053

  Fly   603 DEAHVVRNH--KSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTW-KKWI 664
            ||||.::|.  |......:..|  :::..|||||:||...::::||.||..:.|...:|: :::.
Zfish  1054 DEAHRLKNKNCKLLEGFKLMSL--EHKVLLTGTPLQNTVEELFSLLHFLEPTRFPSENTFMQEFG 1116

  Fly   665 DNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRT 729
            |.|:.....:|..::|.:||||.|..::     ..|..||..:||:.|...:...|:.::
Zfish  1117 DLKTEEQVQKLQAILKPMMLRRLKEDVE-----KKLAPKEETIIEVELTNIQKKYYRAIL----- 1171

  Fly   730 LFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLR 794
                        |.:|::                         .|:.||   :....::|..::.
Zfish  1172 ------------EKNFSF-------------------------LAKGAG---QANVPNLLNTMME 1196

  Fly   795 LRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEID-----LLAQLNKLAITDTSTDGQQSVANA 854
            ||:.|.||.||    .|.|.:.|.|.........:|     ::....||.:.|
Zfish  1197 LRKCCNHPYLI----KGAEEKIMEDFKEVYSPAAVDFHLQAMIQSAGKLVLID------------ 1245

  Fly   855 GDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTS 919
                 .|||.                                       :|:...|.::.||...
Zfish  1246 -----KLLPK---------------------------------------MKAGGHKVLIFSQMVR 1266

  Fly   920 VLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLL 984
            .||||.|:|.:.......::|.:....||..::.|:..::.:.|.||...|||:|:||..|:..:
Zfish  1267 CLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCI 1331

  Fly   985 LLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLT------- 1042
            :.|..||||.:.|||.|.:|:||.|.|.:|:.:..::.|:.:......||.|...||.
Zfish  1332 IFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLITRNSYEREMFDRASLKLGLDKAVLQSMSGRDN 1396

  Fly  1043 ----GAKVS---SKLTIDDL--KGLFG 1060
                |.::.   ||..|:||  :|.:|
Zfish  1397 SLAGGGQMQQQLSKKEIEDLLRRGAYG 1423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	175/799 (22%)
		DEXHc_TTF2	439..686	CDD:350830	70/267 (26%)
chd9	XP_005169069.3	None