Protein Alignment lds and btaf1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_005169589.1
• Gene: btaf1 / 565357
• ZFINID: ZDB-GENE-021025-1
• Length: 1861
• Species: Danio rerio
• Alignment Length: 1009
• Identity: 230/1009 - (22%)
• Similarity: 394/1009 - (39%)
• Gaps: 244/1009 - (24%)

  Fly   155 PTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADS--EVLDDSSGSDVLILSNK----------E 207
            |...|:|...||..:|.    ||....:::...|:  .:::.:.|...|....|          .
Zfish   940 PMLTPSAACPVPPASTP----IQESSKASVAEKDAMHHMVNKTKGIITLYRHQKAAFAITSKRGP 1000

  Fly   208 TPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPA 272
            ||....|:|::|.... .::|....|.....|..|..|...::..:::.|:...:.:.....|..
Zfish  1001 TPKTPKSNTNNDLPVG-GSISTETDESKKPCLIQRRGAEFCLMTVARHFSKELTKTLPYLWESMT 1064

  Fly   273 APRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSD------AEKLFEKVAHKLP---------- 321
            .|.|:.:.:::......:...:.:.:.....:||.:      :::|...:..:||
Zfish  1065 GPLRNALDAQEFDSSQLLKQGDSVAQDLVNSLQVLEVTAGAMSQELIPLLMEQLPLLCTCLQHPY 1129

  Fly   322 -------DKGSQIMKRIDTLRRELAMDEQ---WISAL---RVQQSNVPAVRVVKPTLNPPRAPSI 373
                   .:...::.:|.|:.......||   |:.|:   ..|:..:.|:..|...|:....|.|
Zfish  1130 TAVRHMAARCVGVLSKIATMETMNVFLEQVLPWLGAIDDNTKQEGAIEALACVMEQLDVDIVPYI 1194

  Fly   374 DTL---DWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAED---- 431
            ..|   ....:|:..:.::  :...|..||.  .:.|.||:         .:|.|..::||
Zfish  1195 VLLVVPVLGRMSDPCDSVR--FMATQCFATL--IRLLPLEA---------GIPDPPSMSEDLIRQ 1246

  Fly   432 ----------------------PVGLKVSLMNHQKHALAWMSWRERKLPRGGILADDMGLGKTLT 474
                                  ||.:|..|..:|:..:.|:::. .|....|||.|||||||||.
Zfish  1247 KARERHFLEQLLDGRKLENYKIPVPIKAELRKYQQDGVNWLAFL-NKYKLHGILCDDMGLGKTLQ 1310

  Fly   475 MISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQW 539
            .| .:||                    .|...:.:..|..|:   .|:....::||||.:|...|
Zfish  1311 SI-CILA--------------------GDHFLRAQEYTRTKA---PDSCPLPSIVVCPPTLTGHW 1351

  Fly   540 ESEVESKVSRQKLTVCVHHG--NNRETKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIIL 602
            ..||....|::.|....:.|  ..|......::.::::|.:|.:|..:   :.....:|:...||
Zfish  1352 VDEVGKFCSKEFLNPLHYTGPPTERARLQHQVKKHNLIVASYDVVRND---VEFFRDIKFNYCIL 1413

  Fly   603 DEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWI--- 664
            ||.||::|.|::.|.|:..|...||..|:||||||..|::::|..||...   .|.|.:::.
Zfish  1414 DEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFDFLMPG---FLGTERQFAARY 1475

  Fly   665 --------DNKSAGGQNRLNLL-MKSL-------MLRRTKAQLQSDGKLNSLPNKELRLIEISLD 713
                    |.||:..:....:| |::|       :|||.|     |..|..||.|.::....:|.
Zfish  1476 GKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMK-----DDVLQDLPPKIIQDYYCNLS 1535

  Fly   714 KEEMNVYQTVMTYSRTLFAQFLHQRAERETD-----FNYRSDANKPTYNQIKDPNGAYYKMHEKF 773
            ..::.:|:           .|...||:...|     .:.:.|..||
Zfish  1536 PLQVQLYE-----------DFAKSRAKVNVDDVISTASTQEDEEKP------------------- 1570

  Fly   774 ARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGE----ESQTMGDHSSDSDTPEIDLLAQ 834
                  |.:...| :...|..||::|.||.|:......|    ..|....|||..|......|:.
Zfish  1571 ------KLKATGH-VFQALQYLRKLCNHPALVLTPQHPEYKHITEQLSTQHSSLRDIQHAPKLSA 1628

  Fly   835 LNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQIL 899
            |.:|.:     |.....|.|.|.|     .||.:|:               ||
Zfish  1629 LKQLLL-----DCGLGSAGASDSG-----TEAVVAQ---------------HR------------ 1656

  Fly   900 KTSILKSSDDKAIVVSQWTSVLDILRDHLSK---DGVATLSLNGTIPVKNRQDIVNEFNDRNNQK 961
                       .::..|..|:|||:...|.|   .||..|.|:|::....|..||:.||: :...
Zfish  1657 -----------VLIFCQLKSMLDIVEQDLLKPQLPGVTYLRLDGSVQAGLRHSIVSRFNN-DPSI 1709

  Fly   962 RVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRI 1026
            .||||:...||:||||.||:.::.::..|||..:.||.||.:|:|||:.|.:|:.:...|:|::|
Zfish  1710 DVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKI 1774

  Fly  1027 KGLQDKKLDLADGVLTGAKVS-SKLTIDDLKGLF 1059
            .|||..|:.:|:.|::....| ..:..:.|..||
Zfish  1775 MGLQKFKMTIANTVISQENASLQSMGTEQLLNLF 1808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	199/844 (24%)
		DEXHc_TTF2	439..686	CDD:350830	72/267 (27%)
btaf1	XP_005169589.1	DUF3535	595..1062	CDD:463447	23/126 (18%)
		HEAT repeat	1063..1100	CDD:293787	4/36 (11%)
		HEAT repeat	1110..1146	CDD:293787	3/35 (9%)
		HEAT repeat	1158..1181	CDD:293787	5/22 (23%)
		HEAT repeat	1194..1223	CDD:293787	5/30 (17%)
		HepA	<1241..1790	CDD:440319	173/670 (26%)
		DEXHc_Mot1	1276..1513	CDD:350757	72/267 (27%)