Protein Alignment lds and smarcad1b

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_005155692.3
• Gene: smarcad1b / 563175
• ZFINID: ZDB-GENE-091113-61
• Length: 955
• Species: Danio rerio
• Alignment Length: 1142
• Identity: 249/1142 - (21%)
• Similarity: 443/1142 - (38%)
• Gaps: 321/1142 - (28%)

  Fly    10 SDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQ---SSETAESEK 71
            ||.:.||.::.||:...||       .|..|....|||    ||....:||.:   .::...:..
Zfish    45 SDSDSDSEISGSSMMPVRK-------LRPRKRKAASSA----DEYSVSDEEEEIVVKTKRRPTHS 98

  Fly    72 SDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSITGVRPQ 136
            ......||.:|.:.....::|...|..:..|..|:.:     .|.::||     .|..:.|...:
Zfish    99 RTTRSTSQQAQPAHQKASETVTDIAHPSPLKTSGMAA-----ADSVQQR-----RRQQMCGSSQE 153

  Fly   137 DLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDS-----S 196
            ..|.....:..:|:.:|....:...|.::.:...:|....:|:|...:...| .::||:     .
Zfish   154 SDSRKGGRVSAADDSEEEGQRSKDQERMLRKLQRKFPHLNKNELRDVLQEHD-WLIDDALETLRM 217

  Fly   197 GSDVLILSNKE-----TPIE---ILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTS 253
            .||:::.|..:     ||.:   .::.|...|...|  :|.||..:||:.|.
Zfish   218 FSDLVVESEDDSSQTSTPAKHTRRVAETRPQAQVTK--LSSPPKPKPSRPLD------------- 267

  Fly   254 KNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAH 318
               ...|.|.:.||   |...:.:.:.||:                     :.||:|   ..|.:
Zfish   268 ---GTRTSQRIAKQ---PILAKYTYVSSEE---------------------ECSDSE---ASVVN 302

  Fly   319 KLPDKGS-QIMKRIDTLRREL-------AMDEQWISA---LRVQQSNVPAVRVVKPTLNPPRAPS 372
            .|.|..| |..:.:..|:.|:       ::||..:.|   |:..| .:..:|..|
Zfish   303 GLLDSDSDQSEETLSKLKTEILCFFQSASVDELTLIAGCSLKKAQ-KITELRPFK---------- 356

  Fly   373 IDTLDWDELSEAV--------------NEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLP 423
                .|.:|.:|:              .|:.......:|:  .:..:.::::.::|:...::..|
Zfish   357 ----TWKDLDDAMRRRNGLSAELLAGCREVLKEREVVKGL--MSKCEEISVKLIQDVTQVMDKGP 415

  Fly   424 G----PEVLAEDPVGLKVSLMNHQKHALAWMSW----RERKLPRGGILADDMGLGKTLTMISSVL 480
            |    ||:|:        |....:.:.|..::|    .:.||  .|||||:||||||:..||.:
Zfish   416 GSMTQPEILS--------STFQLKPYQLIGLNWLVLLHQNKL--SGILADEMGLGKTIQAISFL- 469

  Fly   481 ACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVES 545
                .....||                               ..|..|:..|||.|..|..|:..
Zfish   470 ----AHLYQEG-------------------------------NHGPHLITVPASTLDNWVRELNL 499

  Fly   546 KVSRQKLTVCVHHGNNRETKGKYLR--------DYDIVVTTYQIVAREHKSLSAVFGVKWRRIIL 602
            .....|  |.|::|:..:.  ||:|        :|:|:|:||.:........|....:|....:.
Zfish   500 WCPSFK--VLVYYGSADDR--KYMRYEILNQIVEYNIIVSTYNLAIGNSSDRSLFCKLKLEYAVF 560

  Fly   603 DEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTW-KKWIDN 666
            ||.|:::|..|.....:..:..|||..|||||:||..|::.:||.|:..:.|....:. .|....
Zfish   561 DEGHLLKNMNSLRYRHLMAINAKYRLLLTGTPLQNNLLELMSLLNFIMPNMFSSSTSQIAKMFSM 625

  Fly   667 KSAGGQN--------RLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTV 723
            ||:..|:        ...|:||..:|||.|:::     |..||.||.::...::.:.:..:|..:
Zfish   626 KSSEEQSSFERDRITHAKLIMKPFILRRVKSEV-----LKQLPAKEEQVEFCAMSERQQELYSAL 685

  Fly   724 MTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDI 788
                       ||:         .:..:|                         |.|:|:.:
Zfish   686 -----------LHK---------LKHSSN-------------------------GEKRELTN--- 702

  Fly   789 LVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVAN 853
              ::::||::..||.|               |.....|   :.|..::||.:.:.|
Zfish   703 --VMMQLRKMSNHPLL---------------HRQFYTT---EKLKAMSKLMLKEPS--------- 738

  Fly   854 AGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHR-------------------PSSKINMVIQIL 899
            ..|..|.|:.::..:...           |.|||                   .|.|::::.|:|
Zfish   739 HRDADPALIKEDMEVLSD-----------FELHRLCQQYSALHEYQLNTDVLLDSGKLSLLTQLL 792

  Fly   900 KTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVL 964
            .:  ||...|:.::.||:|.:||||...|.........|:|:.|:.:|..::::|| .:....|.
Zfish   793 NS--LKEKGDRVVLFSQFTMMLDILEVFLRHHKHRYNRLDGSTPMSDRIGLIDQFN-TDQDIFVF 854

  Fly   965 LLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGL 1029
            |||..|||:|:||..||.::|.|:..||..:.||:.|.:||||.|.|.:.|.:..|::|..:..:
Zfish   855 LLSTRAGGLGINLTSANVVILHDIDCNPYNDKQAEGRCHRVGQTKTVKVIKLISKDSIEDTMLRI 919

  Fly  1030 QDKKLDLADGVLTGAKVSSKLTIDD-----LKGLFGM 1061
            .::||.| :..:|..:...:.|:.|     ||...|:
Zfish   920 GERKLKL-EQEMTATQDGEEDTLPDDMTTLLKASLGL 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	183/822 (22%)
		DEXHc_TTF2	439..686	CDD:350830	69/267 (26%)
smarcad1b	XP_005155692.3	CUE	179..215	CDD:270465	7/36 (19%)
		ComEA	<329..377	CDD:441164	10/62 (16%)
		HepA	<429..926	CDD:440319	153/634 (24%)