Protein Alignment lds and smarcad1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001015697.1
• Gene: smarcad1 / 548414
• XenbaseID: XB-GENE-492700
• Length: 1003
• Species: Xenopus tropicalis
• Alignment Length: 1178
• Identity: 256/1178 - (21%)
• Similarity: 445/1178 - (37%)
• Gaps: 365/1178 - (30%)

  Fly     2 SSENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSS-- 64
            |:.||:.     ||.|   :|:..:.::.|::..|...|..     ||...::.||.|:.||.
 Frog    31 STPNSQL-----EDHV---TSIPETPEAKRVNNPSLFKKDK-----GVSFLDSDSENEDHQSKSK 82

  Fly    65 -ETAESEKSDESDNSQNSQESEDSEDDSV---RPSA-----------RNTKRKPLGIPSDSEDE- 113
             .:...:.....:|..:...::|||||.:   ||||           :|.:|.....|..:.||
 Frog    83 FSSTHQQSHPREENGTSDSVTDDSEDDYLAVKRPSASTAQVKDGSKYKNLQRLKEIFPKQNNDEL 147

  Fly   114 -----------------------EDELEQRALSPSTRMSI---TGVRPQD---------LSDDDS 143
                                   |....:|.|....:.|.   .|:..|.         .||:||
 Frog   148 LKLIESTSTLDGAVAAGVVLFNKEGSSRKRKLDEVPKDSSPVHEGINGQTKKKKKIDRVSSDNDS 212

  Fly   144 EIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKET 208
            .:...|..::        ||.|.:....|....:.:|.        |||.:...|    ......
 Frog   213 SLSEDDWEKQ--------EASVKKLQRHFPDLDKEELR--------EVLQEHDWS----FHEALE 257

  Fly   209 PIEILSSTDDDATTN---KENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLK---- 266
            .:::.:..:.||..|   ||..:|..|.|.:|: ..:|||.|   |.::|.::...|..:|
 Frog   258 ALKLFAEDETDALQNAAKKEVSNGKEFSRSNKN-DNKSSAKA---KANQNSNKAMAQNGVKKKGK 318

  Fly   267 -QKTSPAAPRRSR-IKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMK 329
             :|.|..|.|.:| ::||:....:....||:..         |..|||.|:...|
 Frog   319 GKKYSENAKRDTRDLESEESASDAGSCLDEDYS---------SGDEKLEEEYKTK---------- 364

  Fly   330 RIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTL----DWDELSEAVNEIKP 390
             |.:..::.::||.::.                |..:..:|..|..|    .|:.|.|.:
 Frog   365 -ILSFLQDASLDELYLI----------------PHCSHKKAQKITELRPFSSWESLFEKM----- 407

  Fly   391 VYTGAQG-------------------MATFNNQKALTLESLKDLHVSLED------LPGPEVLAE 430
              |.:.|                   |...|..:.::....|.:....||      :..|.:::|
 Frog   408 --TKSNGLSEDLIWDCQTLIKEREVVMKLMNKCEEISRTLTKQVTQLTEDGECGWNIEQPSIMSE 470

  Fly   431 DPVGLKVSLMNHQKHALAWMS-WRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDE 494
            :.|     |..:||..|.|:: ..:.|:  ..||||:||||||:..|:.:
 Frog   471 NLV-----LKPYQKIGLNWLALLHKHKV--NMILADEMGLGKTVQAIAFL--------------- 513

  Fly   495 SSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHG 559
                        ....|||       |:  |..|||.|||.:..|..|.....  ..:.:.:::|
 Frog   514 ------------AHLYVTG-------DS--GPHLVVVPASTMDNWIREFNQWC--PSMNILLYYG 555

  Fly   560 NNRETKGKYLR--------DYDIVVTTYQ--IVAREHKSLSAVFGVKWRRI-----ILDEAHVVR 609
            :..|.  |:||        :::::||||.  |.:.|.:||       :||:     :.||.|:::
 Frog   556 SQEER--KHLRYDILNKVVEFNVIVTTYNCAISSAEDRSL-------FRRLKLNFAVFDEGHMLK 611

  Fly   610 NHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDD-------LHTWK-KWIDN 666
            |..:.....:..|..:.|..|||||:||..|::.:||.|:....|..       |.:.| |..|.
 Frog   612 NMSAIRYQHLMTLNARSRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIKRLFSSKAKSTDE 676

  Fly   667 KSAGGQNRL---NLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSR 728
            ::...:.|:   ..:||..:|||.|:::     |..||.|:.::....:.|::..:|..::
 Frog   677 QTIFEKERIAHAKQIMKPFILRRVKSEV-----LKQLPPKQDKIKFCQMSKKQEQLYSDLL---- 732

  Fly   729 TLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLL 793
                                        |::|....|                ..|:.::..:::
 Frog   733 ----------------------------NKLKKSIDA----------------TEKNSELCNVMM 753

  Fly   794 RLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDG 858
            .||::..||.|.......:..:||                  :||.:.:.:         ..|..
 Frog   754 HLRKMANHPLLHRQYYTADRLRTM------------------SKLMLKEPT---------HCDAN 791

  Fly   859 PPLLPDEARIAKASKNLLKRSNPVFNLHR-------------------PSSKINMVIQILKTSIL 904
            |.|:.::..:...           |.|||                   .|.|.|::.::|  |.:
 Frog   792 PDLIFEDMEVMTD-----------FELHRLCNEFTTLSQYKLEKELILDSGKFNILEKLL--SDI 843

  Fly   905 KSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLT 969
            |...|:.::.||:|.:|||:...|.......:.|:|...:..|..:::||| .:....:.|||..
 Frog   844 KKKGDRVVLFSQFTMMLDIIEVFLRHHQHRYVRLDGKTQISERIHLIDEFN-TDMDIFIFLLSTK 907

  Fly   970 AGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKL 1034
            |||:|:||..||.::|.|:..||..:.||:||.:||||.|.|.:.|.:...|:|:.:..:..:||
 Frog   908 AGGLGINLTSANIVILHDIDCNPYNDKQAEDRCHRVGQTKEVKVIKLIGKGTIEESMLKISQQKL 972

  Fly  1035 DLADGVLT 1042
            .|...:.|
 Frog   973 RLEQDMTT 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	179/828 (22%)
		DEXHc_TTF2	439..686	CDD:350830	71/273 (26%)
smarcad1	NP_001015697.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..130		27/111 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..235		14/70 (20%)
		CUE	223..259	CDD:270465	9/47 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..351		23/80 (29%)
		HepA	<471..974	CDD:440319	151/650 (23%)
		DEGH box	605..608		2/2 (100%)