Protein Alignment lds and dom

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Alignment Length: 1386
• Identity: 273/1386 - (19%)
• Similarity: 480/1386 - (34%)
• Gaps: 526/1386 - (37%)

  Fly    33 SKSSRLSKSSRPSSAGVVIDETQSEEE---ESQSSETAESEKSDESDNSQNSQESEDSEDDSVRP 94
            :|.....|.:.......::|:|:...:   |..:...|::...:.|..:...:||    ||..||
  Fly   637 TKIEEKRKQALDQHLSFIVDQTEKFSQQLVEGMNKSVADTPSLNSSRLTSPKRES----DDDFRP 697

  Fly    95 SARNTKRKPLGIPSDSEDEEDEL---EQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQEGPT 156
            .            |.|||:|:.:   |:.|  ...:..:|.:.      .:||:::.|.:.:.|
  Fly   698 E------------SGSEDDEETIAKAEEDA--ADVKEEVTALA------KESEMDFDDFLNDLP- 741

  Fly   157 EAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDAT 221
                     |.|.......::.:..|.|   .:|..|||..|:   ...||      :|.||:.|
  Fly   742 ---------PGYLENRDKLMKEEQSSAI---KTETPDDSDDSE---FEAKE------ASDDDENT 785

  Fly   222 TNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKV 286
            .:|:       |...:.:..:..  ...::...:||...:.|..|.: .|.:|:|
  Fly   786 ISKQ-------EEAEQEIDHKKE--IDELEADNDLSVEQLLAKYKSE-QPPSPKR---------- 830

  Fly   287 VSQVVYDEEMRKLAEKRVQV-SDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRV 350
                      ||||.:..:: ||.:........:..|..::..:.:.|::.:..|:||     ..
  Fly   831 ----------RKLAPRDPELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQ-----DE 880

  Fly   351 QQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFN-----NQKALTLE 410
            |:..:.::..                |.|..|.|..      :|:...|:.|     |..|...|
  Fly   881 QEDGLKSLMA----------------DADATSGAAG------SGSTAGASGNKDDMLNDAAALAE 923

  Fly   411 SLKDLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWM-SWRERKLPRGGILADDMGLGKTLT 474
            ||:.   ....|....|:...|..||.||..:|...|.|: :..||||  .|||||:||||||:.
  Fly   924 SLQP---KGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKL--NGILADEMGLGKTIQ 983

  Fly   475 MISSV--LACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLR 537
            .|:.:  |||..|                           .|          |..|:|.|:|::.
  Fly   984 TIALLAHLACAKG---------------------------NW----------GPHLIVVPSSVML 1011

  Fly   538 QWESEVESKVSRQKLTVCVHHGNNRETKGKYL-----RDYDIVVTTYQIVAREHKSLSAVFGVKW 597
            .||.|.:......|  :..::|:.:|.|.|.:     ..:.:.:|:|::|.::.:|...   .||
  Fly  1012 NWEMEFKKWCPGFK--ILTYYGSQKERKLKRVGWTKPNAFHVCITSYKLVVQDQQSFRR---KKW 1071

  Fly   598 RRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKK 662
            :.:|||||..::|.|||....:.:...:.|..|||||:||..:::::|:.||....|.....:|:
  Fly  1072 KYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKE 1136

  Fly   663 WIDNKSAG---GQ--------NRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEE 716
            |..|...|   |.        .||:.:::..:|||.|.:::     ..:|.|...:|...|...:
  Fly  1137 WFSNPMTGMIEGNMEYNETLITRLHKVIRPFLLRRLKKEVE-----KQMPKKYEHVITCRLSNRQ 1196

  Fly   717 MNVYQTVMTYSRTL--------------------------------------------------- 730
            ..:|:..|:.::|.
  Fly  1197 RYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVC 1261

  Fly   731 -------FAQ---------FLHQRAERETDFNYRSDANKPTYNQIKD-----------PNGAY-Y 767
                   |.|         .||.........:::|....|....|:|           |||.| :
  Fly  1262 DIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRF 1326

  Fly   768 KMHEKFARMA----------GSKKEVKSHDILVLLLR--------LRQI---------CCHPGLI 805
            .:..:.|.:|          |:...::.....::.:|        |:::         ...|.:|
  Fly  1327 HIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIMPMRNLLPSGRVLKRVSASINPVNMALKPVVI 1391

  Fly   806 DAMLDGEESQTMGDHSSDSDTPEIDLL---------AQLN------------------------- 836
            ::::....|.|    ::.|.|..:.:|         :|:|
  Fly  1392 NSVVTTTSSST----TASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATN 1452

  Fly   837 -----------------------KLAITDTSTDGQ---------------------QSVAN---- 853
                                   :..:|.::|.||                     ||:||
  Fly  1453 SGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTE 1517

  Fly   854 ------AGD------------------------------DGPPLLPDEARIA-----KASKNLLK 877
                  |.|                              |..|:..::.|.|     :|::: ||
  Fly  1518 PEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRS-LK 1581

  Fly   878 RS------------------------------------NPVFN---LHRPS-------------- 889
            ||                                    .|||.   ::.||
  Fly  1582 RSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLS 1646

  Fly   890 -------SKI-NMVIQILKTSI------------------------------------LKSSDDK 910
                   .:| |:|.|.|:..:                                    ||.:..:
  Fly  1647 STHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHR 1711

  Fly   911 AIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRV--LLLSLTAGGV 973
            .::.:|.|.:||:|...|:..|...|.|:|:..|:.||.::..|   |..||:  .:||..:|||
  Fly  1712 VLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERF---NGDKRIFCFILSTRSGGV 1773

  Fly   974 GLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLAD 1038
            |:||.||:.::..|..|||.::||||||.:|:||.::|.||:.:...|:|..|....::|..|:|
  Fly  1774 GINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSD 1838

  Fly  1039 GVLTGAKVSS----KLTIDDL 1055
            ..:.|...::    ..||.||
  Fly  1839 MAIEGGNFTTTYFKSSTIKDL 1859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	219/1106 (20%)
		DEXHc_TTF2	439..686	CDD:350830	73/265 (28%)
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	153/693 (22%)
		DEXQc_SRCAP	949..1171	CDD:350761	73/265 (28%)
		SF2_C_SNF	1685..1817	CDD:350180	45/134 (34%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	56/161 (35%)
		HEC1	<1858..>2031	CDD:444066	2/2 (100%)
		SP1-4_N	2486..>2819	CDD:425404