Protein Alignment lds and Rad54l2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001127992.2
• Gene: Rad54l2 / 363135
• RGDID: 1561889
• Length: 1466
• Species: Rattus norvegicus
• Alignment Length: 1138
• Identity: 227/1138 - (19%)
• Similarity: 384/1138 - (33%)
• Gaps: 401/1138 - (35%)

  Fly    53 ETQSEEEESQSSETAESEKSDESD-----------NSQNSQESEDSEDDSVRPSARNTKRKPLGI 106
            |...||||.:.....|.::.||..           .::::|..||.:......|..:::.:|
  Rat    20 EDAEEEEEEEEVAVEEHDRDDEEGLLDDPSLEGMCGTEHAQLGEDGQRPPRCTSTTSSQSEP--- 81

  Fly   107 PSDSED---------EEDELEQRALSPS-TRMSITGVRPQDLSD-----------------DDSE 144
               ||.         .||..::||..|| .|.:|..:..:|..:                 :...
  Rat    82 ---SEQLRHQGKILASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQR 143

  Fly   145 IEYSDEVQEGPTEAPTAEAVV---------PRYTTQFAGNIQNDLHSTIGAADSEV--LDDSSGS 198
            .||:..:...|.|....|.|:         ||...|                  ||  ||.||||
  Rat   144 KEYAAPIPTVPLEFLPEEIVLRASDGPQLPPRVLAQ------------------EVICLDSSSGS 190

  Fly   199 D---------VLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSK 254
            :         :.:.|.:|..:.|:.|::..:..::|...|.  ...:.:|:...:.|..:|
  Rat   191 EDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEEEEKGG--THVNDALNQHDALGRVLV---- 249

  Fly   255 NLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHK 319
            ||:.|.     :::....||:.:|.....|....:.:||..:..|  :|.:.|......  :||.
  Rat   250 NLNHPP-----EEENVFLAPQLARAVKPHQIGGIRFLYDNLVESL--ERFKTSSGFGCI--LAHS 305

  Fly   320 LP-DKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSE 383
            :. .|..|::..||.|.|                 :.||                         :
  Rat   306 MGLGKTLQVISFIDVLFR-----------------HTPA-------------------------K 328

  Fly   384 AVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAED-------PVGLKVSLMN 441
            .|..|.||.|....:|.||..                 ||.||.|..|       |...||.::|
  Rat   329 TVLAIVPVNTLQNWLAEFNMW-----------------LPAPEALPADSKPEEIQPRFFKVHILN 376

  Fly   442 HQKHALA--------WMSWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDS 498
            .:...:|        |:|       .||:|.....:.:.||:..|:...:..:..........|.
  Rat   377 DEHKTVASRAKVTTDWVS-------EGGVLLMGYEMYRLLTLKKSLATGRPKKTKKRSHPVIIDL 434

  Fly   499 DSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRE 563
            |.||.:.:.|:...      :...|.|..:|:|
  Rat   435 DEEDRQQEFRREFE------KALCRPGPDVVIC-------------------------------- 461

  Fly   564 TKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRW 628
                                                   ||.|.::|.::.:|.|:.::|.:.|.
  Rat   462 ---------------------------------------DEGHRIKNCQASTSQALKNIRSRRRV 487

  Fly   629 ALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ----------------NRLNL 677
            .|||.|:||..::.:.::.|:|.........:....:.....||                :.|:.
  Rat   488 VLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHS 552

  Fly   678 LMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERE 742
            |::..:.||....|    |:: ||.||..:|.:.|.:           ..|.|:.||:
  Rat   553 LLEGFVQRRGHTVL----KIH-LPAKEENVILVRLSQ-----------IQRDLYTQFM------- 594

  Fly   743 TDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICC----HPG 803
                                        ::| |..||...:..:.     |:...:||    ||
  Rat   595 ----------------------------DRF-RDCGSSGWLGLNP-----LKAFCVCCKIWNHP- 624

  Fly   804 LIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARI 868
              |.:.:..:.:.:. :..|.|..|:.......:.....|...|:.|.          ||.....
  Rat   625 --DVLYEALQKENLA-NEQDLDVEELGSAGTSTRCPPHGTKVKGEDSA----------LPSSMGE 676

  Fly   869 AKASKNL--------LKRSNPVFNLH--------------RPSSKINMVIQILKTSILKSSDDKA 911
            |..||.|        .:|.|.:....              ..|.|:.::..:::.|:  ...||.
  Rat   677 ATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESV--KLGDKI 739

  Fly   912 IVVSQWTSVLDILRDHLSK---------DG---------VATLSLNGTIPVKNRQDIVNEFNDRN 958
            :|.||..|.|.::.:.|.|         :|         |:...|:|:.|...|:.::|:|||.:
  Rat   740 LVFSQSLSTLALIEEFLGKRDMPCPPGAEGQGAQKWVRNVSYFRLDGSTPAFERERLINQFNDPS 804

  Fly   959 NQKR-VLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTV 1022
            |... :.|||..||.:|:||||||.:::.|..|||..:|||..|:||.||||...||:.:...|:
  Rat   805 NLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTL 869

  Fly  1023 EQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDL 1055
            |::|...|..|..::|.|           :|||
  Rat   870 EKKIYDRQISKQGMSDRV-----------VDDL 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	166/830 (20%)
		DEXHc_TTF2	439..686	CDD:350830	39/270 (14%)
Rad54l2	NP_001127992.2	HepA	109..889	CDD:440319	203/1039 (20%)
		DEXHc_ARIP4	270..546	CDD:350827	70/422 (17%)
		PHA03247	<1111..1429	CDD:223021